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- Title
- Justificacion y diseno del estudio PICNIC: Programa de IntervenCion Nutricional en pacientes hospitalizados por Insuficiencia Cardiaca desnutridos. [Rationale and design of PICNIC study: Nutritional intervention program in hospitalized patients with
- Authors
- Gamez-Lopez,A. L.;Bonilla-Palomas,J. L.;Anguita-Sanchez,M.;Moreno-Conde,M.;Lopez-Ibanez,C.;Alhambra-Exposito,R.;Castillo-Dominguez,J. C.;Villar-Raez,A.;Suarez de Lezo,J.
- Publication Year
- 2014
- Abstract
- Introduction and objectives: Hospitalized patients with heart failure who are malnourished present a worse prognosis than those with an adequate nutritional status. It is unknown whether a nutritional intervention can modify the prognosis of these patients. The aim of this study is to assess the efficacy of a nutritional intervention on morbidity and mortality in hospitalized patients with heart failure who are malnourished. Methods: PICNIC is a multicentre, randomized, controlled trial in which hospitalized patients with heart failure and malnutrition, as defined by the Mini Nutritional Assessment, are randomly assigned to conventional management of heart failure or conventional management of heart failure and an individualized nutritional intervention consisting of 3 points: optimization of diet, specific recommendations, and prescription, if deemed necessary, of nutritional supplements. A sample size of 182 patients for a maximum follow-up of 12 months has been estimated. The primary endpoint is time to death from any cause or rehospitalization because of heart failure. Analysis is by intention to treat. Conclusions: PICNIC study will determine the prognostic impact of a nutritional intervention in hospitalized patients with heart failure who are malnourished. Full English text available from: www.revespcardiol.org/en. (copyright) 2014 Sociedad Espanola de Cardiologia.
- Journals
- Rev Esp Cardiol.
- Volume
- Issue
- Startpage
- Nov 19 [Epub ahead of print]
- Endpage
- Booktitle
- Editors
- City
- Publisher
- Abstract Link
- www.ncbi.nlm.nih.gov/pubmed/24268125
- PDF Link
- pdf.revespcardiol.org/ficheros/eop/S1885-5857(13)00292-2.pdf
- Issnisbn
- 1885-5857
- Reflist
- 0
- Doi
- doi:10.1016/j.recesp.2013.07.014; 10.1016/j.recesp.2013.07.014
- Pmid
- PMID: 24268125
- Keywords
- heart failure;malnutrition;hospital patient;human;prognosis;patient;morbidity;follow up;mortality;sample size;diet;nutritional assessment;randomized controlled trial;prescription;intention to treat analysis;death;hospital readmission;nutritional status;De????
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