Publication details

Title
Correlation of comprehensive geriatric assessment (CGA) with mortality in elderly patients with lung cancer: A single institution cohort analysis.
Authors
Dal Molin,G. Z.;Lima,G. E.;Iennaco,P. S.;Pereira,A. T. A. R.;Felismino,T. C.;Freitas,H. C.;Figueroa,B. C. M.;Sanches,S. M.;Fanelli,M. F.;Dettino,A. L. A.
Publication Year
2013
Abstract
Background: In the last 60 years, >65 y population in Brazil has increased more than eigth-fold, from 1.6 million to more than 13 million people. This shift in demographics has a huge impact in healthcare, specially in oncology. Nevertheless, so far there is no national innitiative focusing oncologic geriatric patients. This study is part of an innitiative to improve oncologic care in geriatric patients in a single institution in Sao Paulo, Brazil. Material and Methods: Since March/12, all patients >70 y admitted at AC Camargo Cancer Center have been submitted to CGA tools: Katz, Lawton, Nutritional Status (Mini nutritional assessment), Depression scales (GDS), comorbidities and polypharmacy analysis. The aims of the study were to assess if CGA could be feasible in daily practice and if it could be useful as a tool in treatment decision making. Statistical analysis used chi-square or Fisher exact tests, when indicated. Survival analysis was performed by Kapplan-Meier curve and group's comparison by the logrank test and Mantel-Cox test. The results here presented refer only to lung cancer patients. Results: From Mar/12 to Feb/13, 73 lung cancer pts were analyzed. Median age at admission was 75 y, 53% male, 47% female. Histology distribution was 57% adenocarcinoma, 22% squamous cell, 12% other non small cell and 9% small cell. Staging distribution was I (10%), II (8%), III (24%), IV (58%). There was an association between mortality and Katz (A vs B/C; p = 0.004), Lawton (27 vs 2; p = 0.44), polypharmacy (<5 vs (greater-than or equal to)5; p = 0.73), age (<79 vs (greater-than or equal to)80; p = 0.95) and sex (male vs female; p = 0.52). Conclusion: In this cohort, the incorporation of CGA tools in daily practice was feasible, able to predict mortality and could be useful in the treatment planning in elderly patients with lung cancer. (Table presented).
Journals
Eur J Cancer.
Volume
49
Issue
2
Startpage
S340-
Endpage
S341 [Poster 1559, Poster Session: Cancer in the Older Patient, 2013 European Cancer Congress, Amsterdam, The Netherlands, Sept 27-Oct 1, 2013]
Booktitle
Editors
City
Publisher
Issnisbn
Reflist
0
Doi
doi:10.1016/S0959-8049(13)70062-5
Pmid
Keywords
mortality;aged;human;lung cancer;cohort analysis;neoplasm;geriatric assessment;nutritional status;Brazil;polypharmacy;geriatric patient;male;female;nutritional assessment;cancer center;malnutrition;nutrition;patient;treatment planning;squamous cell;adenoc????
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