MNA® Literature Database

Welcome to the MNA® Literature Database.  Here you will find valuable information on the extensive research that supports use of the MNA® in the elderly.  Currently there are more than 1100 published research articles that reference the MNA®.  Access links to abstracts of all MNA® articles and references cited on the website using the search function, e.g. select “Abstract” and enter a keyword to search abstracts.

Total Records Found: 1162, showing 10 per page
Link to details 1025
Title Nutritional status of community-dwelling elderly with newly diagnosed Alzheimer's disease: Prevalence of malnutrition and the relation of various factors to nutritional status.
Abstract Objetives: To determine the prevalence of malnutrition and its relation to various factors in community-dwelling elderly with newly diagnosed Alzheimer's disease (AD). Design: Retrospective crosssectional study. Setting: Memory clinic in a rural part of the Netherlands. Participants: 312 Community-dwelling AD patients, aged 65 years or older, were included. Measurements: At the time the diagnosis AD was made, socio-demographic characteristics and data on nutritional status (Mini Nutritional Assessment (MNA)), cognitive function (Mini Mental State Examination (MMSE), Cambridge Cognitive Examination (Camcog)), functional status (Interview for Deterioration in Daily Living Activities in Dementia (IDDD), Barthel Index (BI)) and behaviour (Revised Memory and Behaviour Problems Checklist (RMBPC)) were assessed. Characteristics of well-nourished patients (MNA score >23.5) were compared to characteristics of patients at risk of malnutrition (MNA score 17-23.5). Linear regression analysis was performed to assess the effect of various factors on nutritional status. Results: The prevalence of malnutrition was 0% and 14.1% was at risk of malnutrition. AD patients at risk of malnutrition were more impaired in basic and complex daily functioning than well-nourished AD patients (median IDDD score 41.5 [25th-75th percentile 38.8-48.0] versus median IDDD score 40.0 [25th-75th percentile 37.0-43.0], p = 0.028). The degree of impairment in basic and complex daily functioning (IDDD) was independently related to nutritional status (MNA) (p = 0.001, B = -0.062). Conclusion: One in seven community-dwelling elderly with newly diagnosed AD is at risk of malnutrition. The degree of impairment in daily functioning is independently related to nutritional status. Therefore, assessment of the nutritional status should be included in the comprehensive assessment of AD patients. The relation between daily functioning, nutritional status and AD warrants further investigation. (copyright) 2013 Serdi and Springer-Verlag France.
Authors Droogsma,E.;Van Asselt,D. Z. B.;Scholzel-Dorenbos,C. J. M.;Van Steijn,J. H. M.;Van Walderveen,P. E.;Van Der Hooft,C. S.
Publication Year 2013
Journals J Nutr Health Aging.
Volume 17
Issue 7
Startpage 606-
Endpage 610
Doi doi:10.1007/s12603-013-0032-9
Link to details 1026
Title Valoracion nutricional de la oferta y de la ingesta dietetica en una residencia geriatrica. [Nutritional assessment of meals served and dietary intake in a nursing home].
Abstract Background: Malnutrition is a frequent health problem in nursing homes, mainly due to inadequate food intake. Objectives: To assess and compare the nutritional quality of meals served and dietary intake in a nursing home. Methods: A cross-sectional study was performed in 36 elderly institutionalized in a nursing home. Meals served and dietary intake were quantified by means of a three day weighed record. Nutritional status was assessed with the Mini Nutritional Assessment (MNA); cognitive function with the Mini Mental State Examination by Lobo (MEC); and emotional state with the Geriatric Depression Scale of Yesavage (GDS). Results: Food intake was significantly lower than that served, and both were inadequate in polyunsaturated and monounsaturated fatty acids, (alpha)-linolenic acid, docosahexaenoic acid (DHA), fibre, folate, vitamins B6, D and E, calcium, magnesium, iron, zinc, iodine, copper and potassium. The content of selenium on meals offered was in agreement with recommendations, but intake was below recommended levels. The content of cholesterol and saturated fatty acids in meals served were excessive, and although the intake of saturated fatty acids remained excessive, cholesterol intake was adjusted to the recommendations. Conclusions: Supply and dietary intake were unbalanced and deficient, and intake was significantly lower than the offer.
Authors Dudet Calvo,M. E.
Publication Year 2013
Journals Rev Esp Nutr Comunitaria.
Volume 19
Issue 1
Startpage 20-
Endpage 28
Link to details 1027
Title The pertinence of oral health indicators in nutritional studies in the elderly.
Abstract Background and aim: Studies concerning the more appropriate criteria for evaluating oral health in relation to nutrition in the elderly vary greatly. There is a need to identify the most relevant criteria for classifying dental indicators of mastication in nutritional studies, so these indicators may be considered for epidemiological and clinical purposes. The aim of this study was to explore the associations between nutritional deficit and measures of oral health in a group of elderly. Methods: A convenience sample of independent elderly aged 65 years or more attending two primary care clinics in Beirut, Lebanon was selected. Data were collected from a questionnaire including the Mini-Nutritional Assessment (MNA), Geriatric Oral Health Assessment Index (GOHAI) and questions about perception of xerostomia and chewing problems. The oral examinations recorded decayed, missing and filled teeth (DMFT), the prosthetic status and the number of functional units (FU). Results: The sample was composed of 121 women (mean age: 71.59 (plus or minus) 5.97 years) and 80 men (mean age: 72.74 (plus or minus) 6.98 years). They were allocated to two groups: 85 participants suffering from malnutrition (MNA score < 17, n = 17) or at risk of malnutrition (17 < MNA score < 24, n = 68) and 116 participants with a normal nutritional status (MNA score (greater-than or equal to) 24). Parameters that explain MNA variations were perception of xerostomia (OR = 3.49, 95% CI [1.66-7.34]), number of FU (OR = 2.79, 95% CI [1.49; 5.22]), and GOHAI score (OR = 2.905, 95% CI [1.40; 6.00]). Conclusion: Further studies exploring factors affecting nutrition in the elderly should take into consideration perception of xerostomia, number of FUs and GOHAI score. (copyright) 2013.
Authors El Osta,N.;Hennequin,M.;Tubert-Jeannin,S.;Abboud Naaman,N. B.;El Osta,L.;Geahchan,N.
Publication Year 2013
Journals Clin Nutr.
Startpage May 38 [Epub ahead of print]
Doi doi:10.1016/j.clnu.2013.05.012
Link to details 1028
Title Geriatric assessment and decision-making in trans-catheter aortic valve implantation (TAVI).
Abstract Introduction.- Severe symptomatic aortic stenosis has traditionally been treated with surgical aortic valve replacement (SAVR). SAVR is preferably not performed in patients with high operative risk, mainly elderly patients with comorbid conditions. For the last ten years some of these patients have been offered TAVI. Methods.- We will conduct a prospective observational study with comprehensive geriatric assessment (CGA) of 140 TAVI patients over 70-years-old.Wewill use validated geriatric assessment scales likeMMSE,HADS,MNA,NEADL, BADL and TUG. Based on the results of the CGA we will categorize patients as frail, fit or intermediate and investigate several outcome measures in each of the three groups. We will also establish a TAVI score based on well-known risk factors, CGA and the patients' health resources. We will conduct a qualitative study to examine patients' personal experience with TAVI and the preceding decision-making process. We will make a purposive sample of approximately ten patients and perform semi-structured interviews 2-4 weeks after TAVI. Analysis is by systematic text condensation. Results.- The study is ongoing, we don't have results yet. Primary end point after 6 months in the observational study is number of days at home. Secondary endpoints are death, major stroke, cognitive decline, delirium, number of days in hospital or nursing homes. Outcome measures in the qualitative study will be descriptions of patients' experiences related to TAVI and the decision-making process.
Authors Es,A.;Ahr,A.;Jen,A.;Mas,A.
Publication Year 2013
Journals Eur Geriatr Med.
Volume 4
Issue 1
Startpage S74
Endpage [Poster P182, 9th Congress of the European Union Geriatric Medicine Society (EUGMS), Venice, Italy, October 2-4, 2013]
Doi doi:10.1016/j.eurger.2013.07.244
Link to details 1029
Title Prevalence of geriatric syndromes in Egyptian elderly: Impact of diabetes mellitus and glycemic control.
Abstract Introduction.- Diabetes is theorized to be associated with early or accelerated aging and has been implicated in the pathogenesis of some geriatric syndromes. Because of lack of information about the prevalence of geriatric syndromes in Egyptian elderly, whether diabetics or not, this work was constructed to assess this issue. Also, effect of glycemic control was assessed. Methods.- This was a cross-sectional study that included 200 elderly ((greater-than or equal to)65 years old) participants; 100 type 2 diabetics selected from those attending the diabetes outpatient clinic so that 50 were well controlled (HbA1c (less-than or equal to)7 gm.%) and 50 were poorly controlled (HbA1c > 7 gm.%), and the other 100 participants were non-diabetic elderly recruited from outpatient clinic of Internal medicine. Full history and comprehensive geriatric assessment with special attention to findings suggesting presence of geriatric syndromes, including falls, urinary incontinence, visual impairment, chronic pain, malnutrition, poly-pharmacy and functional disability were performed for every participant. Nutritional status was assessed by the mini-nutritional assessment tool, and assessment of functional ability was done by using the Timed get up and Go test. Results.- Prevalence rates of geriatric syndromes were significantly higher in elderly with uncontrolled diabetes compared to both non-diabetic and well-controlled diabetic elderly (P < 0.001) with insignificant difference between the latter two groups. the number of geriatric syndromes in the participants correlated significantly positively with each of age and HbA1c (P < 0.001), and significantly negatively with the body mass index (BMI) (P < 0.001). Conclusion.- Geriatric syndromes are prevalent in elderly persons, with higher prevalence noticed in diabetics particularly poorly controlled. The higher the age and HbA1c levels,and the lower the BMI, the more the number of geriatric syndromes affecting the elderly. More studies are still needed to clarify this issue.
Authors Esmayel,E. M.;Eldarawy,M. M.;Shoukry,A.;Elnaggar,Y.
Publication Year 2013
Journals Eur Geriatr Med.
Volume 4
Issue 1
Startpage S152
Endpage [Poster P436, 9th Congress of the European Union Geriatric Medicine Society (EUGMS), Venice, Italy, October 2-4, 2013]
Doi doi:10.1016/j.eurger.2013.07.498
Link to details 1030
Title Immune senescence and cancer in elderly patients: Results from an exploratory study.
Abstract BACKGROUND: The challenge of immune senescence has never been addressed in elderly cancer patients. This study compares the thymic output and peripheral blood telomere length in >/=70year old cancer patients. PATIENTS AND METHODS: Fifty-two elderly cancer patients and 39 age-matched controls without personal history of cancer were enrolled. All patients underwent a Comprehensive Geriatric Assessment (CGA), from which a multidimensional prognostic index (MPI) score was calculated. Peripheral blood samples were studied for naive and recent thymic emigrant (RTE) CD4(+) and CD8(+) cells by flow cytometry. T-cell receptor rearrangement excision circle (TREC) levels, telomere length and telomerase activity in peripheral blood cells were quantified by real-time PCR. RESULTS: The percentages of CD8(+) naive and CD8(+) RTE cells and TREC levels were significantly lower in cancer patients than in controls (p=0.003, p=0.004, p=0.031, respectively). Telomere lengths in peripheral blood cells were significantly shorter in cancer patients than in controls (p=0.046) and did not correlate with age in patients, whereas it did in controls (r=-0.354, p=0.031). Short telomere (</=median)/low TREC (</=median) profile was associated with higher risk of cancer (OR=3.68 [95% CI 1.22-11.11]; p=0.021). Neither unfitness on CGA nor MPI score were significantly related to thymic output or telomere length in either group. CONCLUSIONS: Immune senescence is significantly worse in elderly cancer patients than in age-matched controls. The low thymic output and the shorter telomeres in peripheral blood cells of cancer patients may reflect a pre-existing condition which facilitates the onset of malignancies in elderly people.
Authors Falci,C.;Gianesin,K.;Sergi,G.;Giunco,S.;De Ronch,I.;Valpione,S.;Solda,C.;Fiduccia,P.;Lonardi,S.;Zanchetta,M.;Keppel,S.;Brunello,A.;Zafferri,V.;Manzato,E.;De Rossi,A.;Zagonel,V.
Publication Year 2013
Journals Exp Gerontol.
Volume 48
Issue 12
Startpage 1436-
Endpage 1442
Doi doi:10.1016/j.exger.2013.09.011; 10.1016/j.exger.2013.09.011
Link to details 1031
Title Risk of being undernourished in a cohort of community-dwelling 85-year-olds: The OCTABAIX study.
Abstract Objectives: To describe the prevalence of the risk of being undernourished in a community-dwelling population of 85-year-olds, and to study associated factors. Methods: A cross-sectional community-based survey of 328 inhabitants assigned to seven primary healthcare teams was carried out. Geriatric assessment was based on sociodemographic variables, the Barthel Index (BI), the Lawton Index (LI), the Spanish version of the Mini-Mental State Examination, the Charlson Comorbidity Index, chronic diseases, social risk measured by Gijon's Social-Familial Evaluation Scale, prescriptions and blood tests. Nutritional status was assessed using the Mini Nutritional Assessment (MNA). Participants were defined as being at risk of undernourishment when they had a MNA score above or equal to 23.5. A comparative analysis was carried out between patients with and without risk of being undernourished, and a multiple logistic regression analysis was carried out. Results: The prevalence risk of being undernourished was 34.5%. A statistically significant association was found with being female (OR 2.44, 95% CI 1.28-4.54), LI (OR 1.47, 95% CI 1.29-1.66), social risk (OR 1.15, 95% CI 1.02-1.29) and prescription drugs taken (OR 5.58, 95% CI 2.09-14.92). Cardiovascular prescription showed a protective association (OR 4.34, 95% CI 1.78-10.0). No statistical differences between the risks of being undernourished were found in the laboratory analysis. Conclusions: There is a high risk of being undernourished in 85-year-old subjects. This nutritional status was positively associated with being female, disability, increased social risk and a high number of prescription drugs, whereas there was a protective relationship with cardiovascular prescription. In evaluations of nutritional status in the community, a multidisciplinary assessment is more valid than analytical findings. (copyright) 2013 Japan Geriatrics Society.
Authors Farre,T. B.;Formiga,F.;Ferrer,A.;Plana-Ripoll,O.;Almeda,J.;Pujol,R.
Publication Year 2013
Journals Geriatr Gerontol Int.
Startpage Sept 2 [Epub ahead of print]
Doi doi:10.1111/ggi.12142
Link to details 1032
Title Dynapenia in older patients with multiple coexistence diseases.
Abstract Introduction.- The aim of the study was to assess factors associated with muscle weakness and low walking speed, accepted prognostic factor, in older patients with chronic medical conditions. Methods.- In patients aged 60 years and over medical history was obtain, muscle weakness was identified as handgrip strength less than 20 kg in women and less than 30 kg in men and walking speed (V) less than 0.8 m/s. Physical performance assessment included: 6 min walk test (6MWT), V, Timed Up&Go test (TUG), Katz's Index and Lawton scale. Mini Mental State Examination (MMSE) and Mini Nutritional Assessment (MNA) were performed. Inflammatory markers: Il-6, IL-8, osteoprotegerin (OPG), TNF-alfa soluble receptor-2 (STNFR2) and 25OHD were measured. Results.- Muscle weakness was found in 27.2% of 92 patients (mean age 72.8(plus or minus)7.6 years; 58.7% men). Mean number of diseases was 5.43(plus or minus)2.2. Subjects with dynapenia were older (76.56(plus or minus)8.1 vs. 71.4(plus or minus)7.0; P = 0.0036), had higher number of diseases (6.3(plus or minus)2.6 vs. 5.1(plus or minus)2.08; P = 0.03), and taken drugs (8.2(plus or minus)2.9 vs. 6.85(plus or minus)2.35; P = 0.037), lower MNA (23.8(plus or minus)2.9 vs. 25.56(plus or minus)2.6; P = 0.008), MMSE (25.17(plus or minus)4.71 vs. 27.01(plus or minus)2.77; P = 0.02), Tscore (-2.06(plus or minus)1.8 vs. -0.813(plus or minus)1.9; P = 0.03), cope worse in IADL (21.25(plus or minus)4.56 vs. 24.42(plus or minus)2.5; P = 0.0007), ADL (5.69(plus or minus)0.86 vs. 6.0(plus or minus)0; P = 0.003) and worse performed 6MWT (300.08(plus or minus)118.18 vs. 369.15(plus or minus)89.97; P = 0.004), and TUG (15.28(plus or minus)5.42 vs. 10.0(plus or minus)2.53; P < 0.0001). They had lower level of Hb (12.99(plus or minus)1.48 vs. 14.01(plus or minus)1.48; P = 0.004), 25OHD (11.86(plus or minus)5.3 vs. 18.46(plus or minus)15.3, P = 0.04) and higher STNFR2 (3849.25(plus or minus)1540.8 vs. 2905.95(plus or minus)1287.37; P = 0.05). Conclusions.- Dynapenia affects over one fourth of patients with chronic medical conditions and is associated with age, comorbidity, risk of malnutrition, inflammation and low vitamin D status. Muscle weakness is associated with worse physical performance and functional impairment.
Authors Fedyk-Lukasik,M.;Skalska,A.;Gryglewska,B.;Grodzicki,T.
Publication Year 2013
Journals Eur Geriatr Med.
Volume 4
Startpage S85
Endpage [Poster P215, 9th Congress of the European Union Geriatric Medicine Society (EUGMS), Venice, Italy, October 2-4, 2013]
Doi doi:10.1016/j.eurger.2013.07.279
Link to details 1033
Title Motor and non-motor determinants of chronic fatigue in idiopathic Parkinson's disease (IPD).
Abstract Background: Fatigue is one of themost common non-motor symptoms in patients with Parkinson's disease(PD) with significant impact on quality of life. Fatigue has received increasing attention during recent decade; however, few studies have examined the determinant factors of fatigue and little is known about the relationship between fatigue and other motor and non-motor symptoms. Objective: The aims of this study were to evaluate determinant factors relating to fatigue in PD and to compare the strength of measure of association for different non-motor and motor symptoms with fatigue severity. Patients and methods: This cross-sectional study was performed in a movement disorder clinic in Tehran, Iran during 2011-2012. A total number of 54 PD (38 males and 16 females) patients with the mean age of 62.5 (SD=9.1) yr were recruited. Fatigue was scored using the Fatigue Severity Scale (FSS). Other scales were used including PDQ39 (PD-specific QoL), HADS (anxiety & depression), MNA (mininutritional assessment), Schwab & England (activity of daily living) and Hoehn & Yahr scales (level of disability). Results: Patients' score in fatigue had significant correlation with anxiety (r=0.32, P=0.020), depression (r=0.41, P=0.002), disease severity measured by Hoehn & Yahr scale (r=0.36, P=0.007) and activity of daily living described by Schwab & England scale (r= -0.35, P=0.011). Conclusion: Our findings showed that more severe depression is accompanied with more severe fatigue in PD patients. In addition to motor symptoms of PD, anxiety and depression have noticeable relationship with fatigue, which must be considered in management of fatigue in PD patients.
Authors Fereshtehnejad,S. -M;Shafiei Sabet,M.;Farhadi,F.;Hadizadeh,H.;Khaefpanah,D.;Naderi,N.;Rahmani,A.;Delbari,A.;Shahidi,G. A.;Lokk,J.
Publication Year 2013
Journals J Neurol Sci.
Volume 333
Issue 1
Startpage e82
Endpage [Abstract No: 2457, Abstracts of the XXI World Congress of Neurology, Vienna, Austria, Sept 21-26, 2013]
Doi doi:10.1016/j.jns.2013.07.560
Link to details 1034
Title Adequacy of food consumption and nutritional intake of dependent patients in a home care program.
Abstract Background and Objectives: Malnutrition in dependent patients has a high prevalence and it can decrease the quality of life and increase morbidity and mortality. The aim of this study is to describe the food consumption of dependent patients in a home care program and to analyze their nutrient intake adequacy. Methods: Cross-sectional study carried out in 10 Primary Care Centers of the Reus-Tarragona area. The patients of the Home Care Program were included when they had a score between 17-23.5 in the Mini Nutritional Assessment test (MNA), older than 65 and had caregivers. Food consumption was recorded by a food frequency questionnaire. The SPSS/PC program was used for statistical analysis. Results: 192 patients of the Home Care Program participated with a mean age of 85(plus or minus)7.2 years. The average intake of energy was 1801.5(plus or minus)434.3 kcal/day in men and 1694.86(plus or minus)312.1 kcal/day in women, 75.06% and 90.39% respectively of the Spanish recommended nutrient intake (RNI). The macronutrient distribution is 38.1% carbohydrates, 47.9% lipids and 13% proteins. The protein intake covers 86.4% of the RNI. The mean intakes of vitamin B3, vitamin B6, vitamin D, Ca and Fe are below two-thirds of the RNI. However, the probability of inadequate intake of vitamin B12 (3.15) and vitamin C (16.98) are low. Conclusions: Dependent patients had a diet high in fat and low in carbohydrates. The average intake of energy and proteins was adequate, but the main vitamins and minerals were below of the recommendations, except for vitamin B12 and vitamin C.
Authors Fernandez-Barres,S.;Marti,N.;Armengol,T. C.;Anguera,C.;Castelao-Alvarez,A. I.;Martinez-Blesa,T.;Pedret,R.;Basora,J.;Arija,V.
Publication Year 2013
Journals Ann Nutr Metab.
Volume 62
Issue 2
Startpage 74
Endpage [Poster P146, Mediterranean Foods on Health and Disease, World Forum for Nutrition Research Conference, Reus, Spain, May 20-21, 2013]
Doi doi:10.1159/000351281