MNA® Literature Database

Welcome to the MNA® Literature Database.  Here you will find valuable information on the extensive research that supports use of the MNA® in the elderly.  Currently there are more than 1100 published research articles that reference the MNA®.  Access links to abstracts of all MNA® articles and references cited on the website using the search function, e.g. select “Abstract” and enter a keyword to search abstracts.

Total Records Found: 1162, showing 10 per page
Link to details 1015
Title Inappropriate prescribing in elderly patients admitted in the University Hospital of Amiens.
Abstract Objectives: Drug associated adverse effects are frequently encountered in elderly patients. Efforts have been made to assist choose of the best treatment for the elderly. One approach is the avoidance of inappropriate medication. The objectives of the present study were to evaluate the characteristics and prevalence of inappropriate prescribing (before admission and at discharge) according to Laroche's list in elderly patients hospitalized in different hospital units. Patients and Methods: The prescription in primary care and at discharge were analysed in 268 randomized patients in four different geriatric units and seven medicine or surgery units of the university hospital in Amiens. Patients included in this study must have been hospitalized more than 3 days and be older than 75 years. In geriatric units, a geriatric assessment has been carried including Charlson score, malnutrition (mini MNA), cognitive disorders (MMS) and loss of autonomy (ADL). Results: Among 268 patients (84.8 (plus or minus) 5.7 years, 98 men and 170 women), 80 were included in geriatrics and 188 in the other wards. The mean number of prescribed drugs was respectively 7.1 at home and 8.2 at discharge. The majority of patients have a Charlson score more than 4 (mean 6.7 (plus or minus) 2.1), a mean MMS of 17.5 (plus or minus) 7.8, mean MNA 8.5 (plus or minus) 2.8, mean ADL 4.1 (plus or minus) 1.7. In primary care, 198 inappropriate prescriptions according Laroche's criteria were found among 111 patients. At discharge, 181 inappropriate medications were prescribed among 106 patients. The most frequently found inappropriate prescriptions concerned benzodiazepines. The polypathological patients with dementia and malnourished were found at greater risk to inappropriate prescriptions concerned benzodiazepines and related drugs. Polyprescription at discharge were associated with the prescription of inappropriate molecules. Differences in terms of inappropriate prescription between the units have been pointed and specific recommendations performed. Discussion: Inappropriate medications are too frequent in elderly patients including at discharge after a hospitalization. Prescribers need to have additional formation regarding this purpose. This project will be integrated in a larger study performed in the four regional hospitals.
Authors Decoudu,L.;Marquant,B.;Liabeuf,S.;Jouanny,P.;Andrejak,M.;Moragny,J.
Publication Year 2013
Journals Fundam Clin Pharmacol.
Volume 27
Issue 1
Startpage 103
Endpage [Poster Abstract P2-123, 8th Congress of Physiology, Pharmacology and Therapeutics (PT2) (17th Annual Meeting of French Society of Pharmacology and Therapeutics, the 80th Annual Meeting of Society of Physiology, the 34th Pharmacovigilance Meeting, th
Doi doi:10.1111/fcp.12026
Link to details 1016
Title Islevsellik, Yetiyitimi ve Sanullligin Uluslararasi Siniflandirilmasi (ICF) Kapsaminda 65 Yas ve Ustu Bireylerde Sanulllikla Ilgili Sik Rastlanilan Sorunlarin ICF Kontrol Listesi ve Cesitli Olcnullekler Kullanilarak Belirlenmesi. [Identification of c
Abstract Objective: The aim of this study was to investigate the common health related problems in people aged 65 years and older and to evaluate these problems in combination with the International Classification of Functioning (ICF) checklist and the other commonly used tools in geriatrics practice. Materials-Methods: In this population-based, cross-sectional, and descriptive study, a total of 200 people aged 65 years or older who lived in a small town in Istanbul, were randomly selected for the study. Data were collected from participants through a face-to-face interview at home visits. ICF Disability and Health (WHODAS-II), Short Form-36 (SF-36), Mini-Mental State Examination, Geriatric Depression Scale, Barthel Index, and Mini Nutritional Assessment were used for evaluating functioning, disability, quality of life, cognitive functions, depression, dependence in the activities of daily living, and nutrition. Results: The mean age of the participants was 72.3(plus or minus)5.3 years. The body functions component of the ICF checklist had the largest number of the impaired categories. The most impaired categories were 'energy, and drive functions' (78.5%) and 'carrying and moving objects' (54.5%), for body functions component and activities and participation component, respectively. The most impaired domain of WHODAS-II was the nullgetting aroundnull domain. The most impaired SF-36 subscale was the emotional role. Severe cognitive impairment and depression rates were 6.0 and 24.0%, respectively. While the risk of malnutrition was found in 9.5% of the sample, 3.0% had definite malnutrition. Conclusion: In this selected sample of persons aged 65 years or older, impairments particularly in mental functions, sensory functions, and pain and domestic life areas were identified. In addition to these findings, many of the persons had different levels of dependence, malnutrition, depression and cognitive decline. Further research should include studies with more participants to investigate health related problems of elderly people for comprising new approaches on rehabilitation.
Authors Dernek,B.;Esmaeilzadeh,S.;Oral,A.
Publication Year 2013
Journals Turk Fiz Tip Rehab Derg.
Volume 59
Issue
Startpage 222
Endpage [Abstract S-002, 24th National Physical Medicine & Rehabilitation Congress/Ulusal Fiziksel T?p ve Rehabilitasyon Kongresi, Antalya, Turkey, March 27, 31, 2013]
Doi
Link to details 1017
Title Nutrition et maladie de Parkinson. [Nutrition in Parkinson's disease].
Abstract About 143,000 patients suffered from Parkinson's disease (PD) in France in 2005. The main nutritional issues are undernutrition, the need of adaptation of protein intakes and the weight gain after deep brain stimulation. Malnutrition is linked to the disease itself and treatments. Handicap, psychological troubles, swallowing disorders, taste and smell disorders, gastroparesis and constipation are the main causes of dietary intake insufficiency. Malnutrition care is not specific. Energy expenditure is probably enhanced by hypertony and abnormal movements, and depends on patient responses to treatments. One out of four PD patients can be undernourished, thus an early screening of undernutrition is mandatory. Body Mass Index (BMI), weight variation and Mini Nutritional Assessment(registered trademark) (MNA(registered trademark)) are the tools usually used in PD. Except for protein intakes, nutritional care has no specificity. Indeed, several aminoacids and levodopa compete for intestinal absorption and transport across blood-brain barrier. When treatments have a low efficiency, or if disease worsens, protein intake has to be increased for dinner and limited for other meals, levodopa has to be taken 20 to 30minutes before meals, and in front of severe neurological troubles, daily protein intake can be decreased. Deep brain stimulation is rapidly followed by an increase in weight, sometimes complicated with dyslipidemia or diabetes. Obesity may increase the handicap. Swallowing disorders are the main cause of mortality. When enteral nutrition is mandatory, the gastrostomy has not to be early discussed. (copyright) 2013 Elsevier Masson SAS.
Authors Desport,J. -C;Jesus,P.;Fayemendy,P.;Pouchard,L.
Publication Year 2013
Journals Nutr Clin Metab.
Volume 27
Issue 2
Startpage 87-
Endpage 91
Doi doi:10.1016/j.nupar.2013.04.001
Link to details 1018
Title Screening for malnutrition among nursing home residents - A comparative analysis of the Mini Nutritional Assessment, the Nutritional Risk Screening, and the Malnutrition Universal Screening Tool.
Abstract Background: The European Society for Clinical Nutrition and Metabolism (ESPEN) has recommended the Mini Nutritional Assessment (MNA(registered trademark)), the Nutritional Risk Screening 2002 (NRS), and the Malnutrition Universal Screening Tool (MUST) for nutritional screening in various settings and age groups. While in recent years all three tools have been applied to nursing home residents, there is still no consensus on the most appropriate screening tool in this specific setting. Aim: The present study aims at comparing the MNA, the NRS, and the MUST with regard to applicability, categorization of nutritional status, and predictive value in the nursing home setting. Method: MNA, NRS, and MUST were performed on 200 residents from two municipal nursing homes in Nuremberg, Germany. Follow-up data on infection, hospitalization, and mortality were collected after six and again after twelve months. Results: Among 200 residents (mean age 85.5 (plus or minus)7.8 years) the MNA could be completed in 188 (94.0%) and the NRS and MUST in 198 (99.0%) residents. The prevalence of 'malnutrition' according to the MNA was 15.4%. The prevalence of 'risk of malnutrition' (NRS) and 'high risk of malnutrition' (MUST), respectively, was 8.6% for both tools. The individual categorization of nutritional status showed poor agreement between NRS and MUST on the one hand and MNA on the other. For all tools a significant association between nutritional status and mortality was demonstrated during follow-up as classification in 'malnourished', respectively 'high risk of malnutrition' or 'nutritional risk', was significantly associated with increased hazard ratios. However, the MNA showed the best predictive value for survival among well-nourished residents. Conclusion: The evaluation of nutritional status in nursing home residents by MNA, NRS, and MUST shows significant differences. This observation may be of clinical relevance as nutritional intervention is usually based on screening results. As the items of the MNA reflect particularities of the nursing home population, this tool currently appears to be the most suitable one in this setting. (copyright) 2013 Serdi and Springer-Verlag France.
Authors Diekmann,R.;Winning,K.;Uter,W.;Kaiser,M. J.;Sieber,C. C.;Volkert,D.;Bauer,J. M.
Publication Year 2013
Journals J Nutr Health Aging.
Volume 17
Issue 4
Startpage 326-
Endpage 331
Doi doi:10.1007/s12603-012-0396-2
Link to details 1019
Title Inflammation, functional status, and weight loss during recovery from cardiac surgery in older adults: A pilot study.
Abstract Objective: To determine the nutritional, inflammatory, and functional aspects of unintentional weight loss after cardiac surgery that warrant further investigation.Research Methods and Procedures: Twenty community-dwelling adults > 65 years old undergoing cardiac surgery (coronary artery bypass graft [CABG] or CABG + valve) were recruited for this prospective longitudinal (preoperative and 4-6 weeks postdischarge) pilot study. Anthropometrics (weight, standing height, and mid-arm and calf circumference), nutritional status (Mini-Nutritional Assessment [MNA]), appetite, physical performance (timed chair stand), muscle strength (hand grip) and functional status (basic and instrumental activities of daily living), and inflammatory markers (plasma leptin, ghrelin, interleukin [IL]-6, high-sensitivity[hs] C-reactive protein, and serum albumin and prealbumin) were measured.Results: Participants who completed the study (n = 11 males, n = 3 females) had a mean age 70.21 +/- 4.02 years. Of these, 12 lost 3.66 +/- 1.44 kg over the study period. Weight, BMI, activities of daily living, and leptin decreased over time (p < .05). IL-6 increased over time (p < .05). Ghrelin, hs-CRP, and timed chair stand increased over time in those who underwent combined procedures (p < .05). Grip strength decreased in those who developed complications (p = .004). Complications, readmission status, and lowered grip strength were found in those with low preoperative MNA scores (p < .05).Conclusion: After cardiac surgery, postdischarge weight loss occurs during a continued inflammatory response accompanied by decreased physical functioning and may not be a positive outcome. The impacts of weight loss, functional impairment, and inflammation during recovery on disability and frailty warrant further study.
Authors Dimaria-Ghalili,R. A.;Sullivan-Marx,E. M.;Compher,C.
Publication Year 2013
Journals Biol Res Nurs.
Volume
Issue
Startpage Sept 19 [Epub ahead of print]
Endpage
Doi doi:10.1177/1099800413503489
Link to details 1020
Title Nutritional care in a nursing home in Italy.
Abstract Introduction: Malnutrition is a clinical condition due to the imbalance among needs, intake and use of nutrients, leading to the increase of morbidity and mortality, and to the impairment of quality of life. Even in industrialized countries undernutrition is becoming an alarming phenomenon, especially involving elderly institutionalized subjects. A multicentric study called PIMAI (Project Iatrogenic MAlnutrition in Italy), was carried out in Italy over 2005. The aims of this study were to determine the prevalence of malnutrition in hospitals and in nursing care homes (NH), to assess the level of nutritional attention and to measure the perceived quality in food and nutritional care. This paper represents a preliminary analysis of data collected in a NH included in the PIMAI project. Materials and methods: A total of 100 subjects (29 males and 71 females, aged 80.2(plus or minus)10 years), were recruited from January to June 2005 at the Clinical Rehabilitation Institute "Villa delle Querce" in Nemi (Rome), among patients in the NH facility. All the participants underwent a multidimensional geriatric evaluation (considering nutritional, clinical, functional and cognitive parameters), and a survey on "perceived quality" of nutritional care. Results and discussion: According to nutritional status defined by the Mini Nutritional Assessment(registered trademark), data analysis showed a high prevalence of malnutrition (36%) especially related to advanced age, chewing, cognitive and functional impairments. Patients seemed to consider nutrition to be important for their health; on the other hand, they were not thoroughly satisfied with the quality of food. Particularly, it was observed scarce attention to nutritional status from medical and nursing staff. Conclusions: Our study confirms the need to pay greater attention to nutritional status in elderly institutionalized subjects. Medical and nursing teams need to be aware of the importance to perform an evaluation of nutritional status in these subset of subjects. (copyright) 2013 Donini et al.
Authors Donini,L. M.;Neri,B.;De Chiara,S.;Poggiogalle,E.;Muscaritoli,M.
Publication Year 2013
Journals PLoS ONE.
Volume 8
Issue 2
Startpage
Endpage
Doi doi:10.1371/journal.pone.0055804
Link to details 1021
Title Agreement between different versions of MNA.
Abstract Malnutrition occurs frequently in the elderly with important clinical and functional consequences. Moreover, the treatment of malnutrition in the elderly may be effective if clinical and nutritional interventions are performed in the early stages. Therefore the early identification of the risk of malnutrition using validated and handy tools plays a pivotal role in terms of clinical outcome. Mini Nutritional Assessment (MNA) was validated for this purpose since many years but it is still ongoing the debate over whether the use of different items in certain clinical conditions can be effective without affecting the validity of the nutritional status evaluation. The aim of this study was to assess the agreement between different versions of MNA in the evaluation of nutritional risk in elderly subjects. Methods: 522 subjects, 345 women and 177 men, were recruited from nursing homes or were free living in three different regions in Italy. All subjects underwent a multidimensional geriatric evaluation, addressed especially to nutritional status. We compared three different versions of MNA: the "original" version; a "proportional" MNA (MNA-P) in which the total MNA score was replaced by the ratio between the maximum score that each subject could obtain without including the body mass index (BMI) and the total original MNA score; and a third version in which calf circumference (CC) and mid-upper arm circumference (MAC) were used instead of BMI. Results: According to the original MNA, a high prevalence of malnutrition was found out in both genders (26% of women and 16.3% of men); both the versions of MNA, in which BMI was not considered, showed a good predictive value compared to original MNA. In particular, the MNA-P. showed an overall efficiency equal to 89,1% with specificity and positive predictive value respectively equal to 97.5% and 95.2%. MNA-CC-MAC showed even better results in terms of overall efficiency (91.4%), sensitivity (81.1%), specificity (97.1%), positive and negative predictive values (94.2% and 94.4%, respectively). Conclusion: The different versions of MNA gave similar results in the classifications of subjects and in comparison with nutritional and biochemical parameters. Moreover MNA versions that did not considered BMI seem to be more effective in singling out subjects with risk factors related to malnutrition (disability, reduced strength and calf circumference, anaemia). (copyright) 2013 Serdi and Springer-Verlag France.
Authors Donini,L. M.;Poggiogalle,E.;Morrone,A.;Scardella,P.;Piombo,L.;Neri,B.;Cava,E.;Cucinotta,D.;Barbagallo,M.;Pinto,A.
Publication Year 2013
Journals J Nutr Health Aging.
Volume 17
Issue 4
Startpage 332-
Endpage 338
Doi doi:10.1007/s12603-013-0005-z
Link to details 1022
Title Postmenopozal Osteoporotik ve Osteopenik Kadinlarda Vucut Kompozisyonu, Beslenme, Fonksiyonel Durum ve Yasam Kalitesi Arasindaki Iliski. [The correlation between the body composition, nutrition, functional status and quality of life in osteoporotic a
Abstract Objective: To investigate the differences between the body composition, nutrition, functional status and quality of life in osteoporotic and osteopenic women. Materials-Methods: 100 osteoporotic (group 1), 102 osteopenic (group 2) patients were included in the study. The patients underwent bone mineral density (BMD) measurements (L1-L4 vertebrae, femoral neck, femur total) and body composition measurements consisting of fat tissue mass (FTM), lean tissue mass (LTM) and bone mineral content (BMC) with dual-energy X-ray absorptiometry (DXA) method. Nutritional status of the patients was evaluated by the Mini Nutrition Assessment (MNA), their functional status by Nottingham Extended Activities of Daily Living Scale (NEADLS) and their quality of life by ECOS-16, and their depression status by Beck Depression Inventory (BDI). Results: In the Group 1, FTM, LTM and BMC were statistically significantly lower than Group 2 (p0.05). There were significant correlations between the MNA and FTM, LTM, BMC and L1-L4, femoral neck and femur total BMD values (p<0.05). There was no correlation between the functional status evaluation and the body components, there was a positive correlation between the functional status evaluation and BMD and a statistically significant negative correlation was found between the functional status evaluation and the age (p<0.05). Conclusion: In this study we identified that nutritional status is both related to the body composition and to BMD; functional status was related to the age and BMD. Depression was more significant in the osteoporotic group; however this was not seen to affect the quality of life.
Authors Donullu,B.;Sirzai,H.;Usen,A.;Yilmaz,F.;Kuran,B.
Publication Year 2013
Journals Turk Fiz Tip Rehab Derg.
Volume 59
Issue
Startpage 384
Endpage [Abstract P245, 24th National Physical Medicine & Rehabilitation Congress/Ulusal Fiziksel T?p ve Rehabilitasyon Kongresi, Antalya, Turkey, March 27, 31, 2013]
Doi
Link to details 1023
Title Association between nutritional status (MNA(registered trademark)-SF) and frailty (SHARE-FI) in acute hospitalised elderly patients.
Abstract Objective: This study aimed to explore the association between the impaired nutritional status and frailty in acute hospitalised elderly patients by using two tools, the MNA(registered trademark)-SF (Mini Nutritional Assessment(registered trademark) short-form) and the SHARE-FI (Frailty Instrument for Primary Care of the Survey of Health, Ageing and Retirement in Europe). Design: Cross-sectional study. Setting: Acute hospitalised, community-dwelling elderly patients were recruited at internal medicine wards in Vienna, Austria. Participants: 133 men (39%) and women (61%) aged 74 (65-97) years. Measurements: MNA(registered trademark)-SF was used to investigate malnutrition (<7 points) and patients at risk of malnutrition (8 to 11 points). By using the SHARE-FI, subjects were classified as frail, pre-frail or robust. A factor analysis was applied to identify overlaps between the MNA(registered trademark)-SF and SHARE-FI items. Internal consistency of different dimensions was assessed by using Cronbach's Alpha. Results: Malnutrition or risk of malnutrition was found in 76.7% of the total sample and in 46.8% of robust, in 69.0% of pre-frail, and in 93.0% of frail participants. Frailty or prefrailty was found in 75.9% of the total sample and in 45.1% of the subjects with no risk of malnutrition, in 80.9% of subjects at risk of malnutrition, and in 94.1% of malnourished patients. The two used tools show overlaps in three dimensions: (1) nutrition problems, (2) mobility problems and (3) anthropometric items with a moderate to strong internal consistency (Cronbach's Alpha of 0.670, 0.834 and 0.946, respectively). 64.7% of the total sample (79.5% of frail and 87.9% of malnourished subjects) would participate in a home-based muscle training and nutritional intervention program. Conclusions: This study underlines the association and the overlap between frailty and impaired nutritional status. There is a high readiness to participate in a program to tackle the problems associated with malnutrition and frailty, especially in those, who would benefit most from it. (copyright) 2013 Serdi and Springer-Verlag France.
Authors Dorner,T. E.;Luger,E.;Tschinderle,J.;Stein,K. V.;Haider,S.;Kapan,A.;Lackinger,C.;Schindler,K. E.
Publication Year 2013
Journals J Nutr Health Aging.
Volume
Issue 21
Startpage 1-
Endpage 6
Doi doi:10.1007/s12603-013-0406-z
Link to details 1024
Title Prevalence of malnutrition in elderly over 75 years old with hip fracture.
Abstract Background.- In the elderly, malnutrition might increase the occurrence of falls and fractures. Despite the European Society of Parenteral and Enteral Nutrition's recommendations, screening of malnutrition in the elderly hospitalized for hip fracture seems poorly achieved. The Mini Nutritional Assessment (MNA) is probably the best tool to detect malnutrition in peri-operative context. The aim of this study was to determine the prevalence of malnutrition in elderly patients with hip fracture. Methods.- A prospective study was conducted (May to September 2012), including patients over 75 years old consecutively admitted for hip fracture in an Orthopedic unit of the Grenoble University Hospital. Malnutrition was defined by a MNA< 17/30 and risk of malnutrition by a score between 17 and 23.5/30. Comorbidities (CIRS-G), cognitive (MMSE) and functional status (BADL), and length of hospital stay were collected. A univariate analysis was set. Results.- Fifty patients were included (mean age 86,1 y). The prevalence of malnutrition was 28% and risk of malnutrition was 58%. Malnourished patients had a higher CIRS-G (P < 0.01) and a higher number of severe comorbidities (P < 0.01). Their mean MMSE and BADL were lower (P < 0.01). A higher length of stay was associated with malnutrition (P = 0.01). Conclusions.- Our study confirms a high prevalence of malnutrition in elderly hospitalized for hip fracture but suggests also that malnutrition increases the length of stay. Yet, early screening of malnutrition in the elderly should be done. Interventional studies are needed to determine whether management of malnutrition may improve early and long-term outcomes.
Authors Drevet,S.;Maziere,S.;Bioteau,C.;Couturier,P.;Tonetti,J.;Gavazzi,G.
Publication Year 2013
Journals Eur Geriatr Med.
Volume 4
Issue 1
Startpage S132-
Endpage S133 [Poster P372, 9th Congress of the European Union Geriatric Medicine Society (EUGMS), Venice, Italy, October 2-4, 2013]
Doi doi:10.1016/j.eurger.2013.07.436