MNA® Literature Database

Welcome to the MNA® Literature Database.  Here you will find valuable information on the extensive research that supports use of the MNA® in the elderly.  Currently there are more than 1100 published research articles that reference the MNA®.  Access links to abstracts of all MNA® articles and references cited on the website using the search function, e.g. select “Abstract” and enter a keyword to search abstracts.

Total Records Found: 1162, showing 10 per page
Link to details 1187
Title Assessing the nutritional status of elderly Chinese lung cancer patients using the Mini-Nutritional Assessment (MNA(registered trademark)) tool.
Abstract Purpose: This study assessed the nutritional status of elderly Chinese lung cancer inpatients using a revised version of the Mini-Nutritional Assessment (MNA(registered trademark)) tool. Patients and methods: The revised version of the MNA tool was used to assess the nutritional status of 180 elderly Chinese lung cancer inpatients prior to their scheduled surgery between June 2010 and July 2011. Patients' demographic data, anthropometric parameters, and biochemical markers were collected and analyzed. Results: Among the 180 inpatients who underwent the MNA, 9% were malnourished (MNA score < 19), 33% were at risk of malnutrition (MNA score 19-23), and 58% were well nourished (MNA score (greater-than or equal to) 24). There was significant correlation between the MNA scores of patients who were malnourished, at risk of malnutrition, and well nourished (P < 0.001), as well as between total MNA score and most MNA questions. The three patient groups with different nutritional statuses differed significantly in their responses to anthropometrics and global, diet, and subjective assessments. Conclusion: Incidence rates of malnutrition prior to surgery are high among elderly Chinese lung cancer inpatients. The revised MNA is a valid and reliable tool that can be used to assess and prevent malnutrition among these inpatients. (copyright) 2013 Zhang et al, publisher and licensee Dove Medical Press Ltd.
Authors Zhang,L.;Su,Y.;Wang,C.;Sha,Y.;Zhu,H.;Xie,S.;Kwauk,S.;Zhang,J.;Lin,Y.;Wang,C.
Publication Year 2013
Journals Clin Interventions Aging.
Volume 8
Issue
Startpage 287-
Endpage 291
Doi doi:10.2147/CIA.S41941
Link to details 975
Title Prognostic value of geriatric assessment in older patients with advanced breast cancer receiving chemotherapy.
Abstract Introduction: The prognostic value of geriatric assessment in older patients with breast cancer treated with chemotherapy is largely unknown. Methods: Fifty-five patients with advanced breast cancer aged 70 years or older were assessed by Mini Nutritional Assessment (MNA), Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE), Groningen Frailty Indicator (GFI) and Mini Mental State Examination (MMSE). Levels of albumin, hemoglobin, creatinine and lactate dehydrogenase were measured. Patients completing at least four cycles of chemotherapy were reassessed by GFI and MMSE and mortality was evaluated using Cox regression analysis. Results: The mean age was 76 year (SD 4.8). Inferior MNA and GFI scores were associated with increased hazard ratios for mortality: 3.05 (95% confidence interval [CI]: 1.44-6.45; p=0.004) and 3.40 (95% CI: 1.62-7.10; p=0.001), respectively. Physical aspects of frailty worsened during the course of chemotherapy. Laboratory values were not associated with assessment scores nor were they predictive for mortality. Conclusions: Malnutrition and frailty, rather than cognitive impairment and laboratory values, were associated with an increased mortality risk in these elderly breast cancer patients with advanced breast cancer. (copyright) 2013 Elsevier Ltd.
Authors Aaldriks,A. A.;Giltay,E. J.;le Cessie,S.;van der Geest,L. G. M.;Portielje,J. E. A.;Tanis,B. C.;Nortier,J. W. R.;Maartense,E.
Publication Year 2013
Journals Breast.
Volume 22
Issue 5
Startpage 753-
Endpage 760
Doi doi:10.1016/j.breast.2013.01.011
Link to details 976
Title Frailty and malnutrition predictive of mortality risk in older patients with advanced colorectal cancer receiving chemotherapy.
Abstract Introduction: In general, geriatric assessment (GA) provides the combined information on comorbidity and functional, nutritional and psychosocial status and may be predictive for mortality outcome of cancer patients. The impact of geriatric assessment on the outcome of older patients with colorectal cancer treated with chemotherapy is largely unknown. Methods: In a prospective study, 143 patients with colorectal cancer who were 70. years and older were assessed before chemotherapy by Mini Nutritional Assessment (MNA), Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE), Groningen Frailty Indicator (GFI) and Mini Mental State Examination (MMSE). Results: Fifty-four (38%) patients received adjuvant chemotherapy and 89 (62%) patients received palliative chemotherapy. Malnutrition and frailty were prevalent in 39 (27%, assessed by MNA) and 34 (24%, by GFI) patients, respectively; whereas cognitive impairment was prevalent in 19 (13%, by IQCODE) and 11 (8%, by MMSE) patients, respectively. In patients with palliative chemotherapy, poor MNA scores were associated with receiving less than 4. cycles of chemotherapy (p = 0.008). Poor MNA and GFI scores were associated with increased hazard ratios (HR) for mortality for patients with palliative chemotherapy: HR = 2.76 (95% confidence interval [CI]: 1.60-4.77; p < 0.001) and HR = 2.72 (95% CI: 1.58-4.69; p < 0.001), respectively, after adjustment for several clinical parameters. Conclusions: Malnutrition and frailty were strongly associated with an increased mortality risk in patients who underwent palliative chemotherapy. Furthermore, a poor score on MNA was predictive for less tolerance of chemotherapy. Our findings may help the oncologist in future decision making and advice for elderly patients with colorectal cancer. (copyright) 2013 Elsevier Inc.
Authors Aaldriks,A. A.;van der Geest,L. G. M.;Giltay,E. J.;le Cessie,S.;Portielje,J. E. A.;Tanis,B. C.;Nortier,J. W. R.;Maartense,E.
Publication Year 2013
Journals J Geriatr Oncol.
Volume 4
Issue 3
Startpage 218-
Endpage 226
Doi doi:10.1016/j.jgo.2013.04.001
Link to details 977
Title Malnutrition in the elderly: A narrative review.
Abstract The focus of nutrition is often on healthy diets and exercise to minimise the risk of developing lifestyle diseases such as cancer, diabetes and cardiovascular disease. However, during the shift into older years often the nutrition priorities change towards meeting increased nutrient needs with less energy requirements, and minimising lean muscle loss. There are several causes of general malnutrition in the elderly that lead to depletion of muscle including starvation (protein-energy malnutrition), sarcopenia and cachexia. The prevalence of protein-energy malnutrition increases with age and the number of comorbidities. A range of simple and validated screening tools can be used to identify malnutrition in older adults, e.g. MST, MNA-SF and 'MUST'. Older adults should be screened for nutritional issues at diagnosis, on admission to hospitals or care homes and during follow up at outpatient or General Practitioner clinics, at regular intervals depending on clinical status. Early identification and treatment of nutrition problems can lead to improved outcomes and better quality of life. (copyright) 2013 Elsevier Ireland Ltd. All rights reserved.
Authors Agarwal,E.;Miller,M.;Yaxley,A.;Isenring,E.
Publication Year 2013
Journals Maturitas.
Volume 76
Issue 4
Startpage 296-
Endpage 302
Doi doi:10.1016/j.maturitas.2013.07.013
Link to details 978
Title Nutrition assessment in advanced heart failure patients evaluated for ventricular assist devices or cardiac transplantation.
Abstract Background: Malnutrition has been shown to affect clinical outcomes in patients with heart failure. The aim of this study was to analyze the incidence of malnutrition and to assess its prognostic significance in patients with advanced heart failure (AHF) (being evaluated for left ventricular assist device [LVAD] or cardiac transplant) based on nutrition status as assessed by the Mini Nutritional Assessment (MNA). Methods: A retrospective analysis was conducted on 154 patients. During evaluation, a complete nutrition assessment was performed, and diagnosis of malnutrition and risk of malnutrition was done with the MNA. Its possible independent association with mortality was assessed. Results: The mean (SD) age of the patients was 59.3 (14.1) years, with 76% men. Twenty-two percent were classified as malnourished, 68% at risk of malnutrition, and 10% well nourished. The mortality in the 3 groups was 26.5%, 42.0%, and 6.7%, respectively (P =.02). In the multivariate logistic regression analysis, the undernutrition state (malnourished + at risk) was an independent predictor of mortality (odds ratio, 7.9; confidence interval, 1.01-62.30; P =.04). Conclusions: The state of undernutrition is an independent predictor of mortality in patients with AHF. Early recognition of undernutrition through use of the MNA may affect the long-term prognosis of these patients by enabling early intervention. (copyright) 2012 American Society for Parenteral and Enteral Nutrition.
Authors Aggarwal,A.;Kumar,A.;Gregory,M. P.;Blair,C.;Pauwaa,S.;Tatooles,A. J.;Pappas,P. S.;Bhat,G.
Publication Year 2013
Journals Nutr Clin Prac.
Volume 28
Issue 1
Startpage 112-
Endpage 119
Doi doi:10.1177/0884533612457948
Link to details 979
Title The geriatric depression scores on nutritional status, cognitive abilities and anthropometric indices in elderly population of Shiraz, Iran.
Abstract Background: Malnutrition and depression are highly prevalent in the elderly and can lead to unfavorable outcomes. The Aims of current study were to determine the association between malnutrition and depression and also to find any correlation of depression with some anthropometric indices, cognitive abilities in free living elderly residents of Shiraz, Iran. Methods: Using cluster sampling in a cross-sectional design, 337 elderly subjects (193 females) participated in this study. Depressive symptoms and nutritional status were determined by the Geriatric Depression Scale (GDS) and the Mini-Nutritional Assessment (MNA) scores questionnaires respectively. Anthropometric indices were measured all in standard situations. Pearson correlation coefficients were calculated for linear relations between variables. Results: From the total subjects entered the study, 43.62% were depressed which 48.01% of them were malnourished or at risk of malnutrition. GDS had a significant negative dependence with the MNA for the entire sample (r = -0.58, p-value<0.0001). However, there was no significant correlation between age and GDS or MNA scores. Moreover, the mean GDS scores differed significantly between men and women (p-value<0.05), and prevalence of depression was higher among women. Depression as it may slow the rate of decline in cognitive and motor abilities Conclusion: The results of the present study revealed high prevalence of depression and malnutrition among old subjects. Moreover, Depression was associated with worsening of nutritional status. The mechanism of this association needs further study.
Authors Ahmadi,S. M.;Keshavarzi,S.;Refahi,Z.;Lankarani,K. B.
Publication Year 2013
Journals J Psychophysiol.
Volume 27
Issue 1
Startpage 63
Endpage [Poster Session 1, Lifestyle, occupation, disease, interventions; Poster 27, Abstracts of the International Conference “Aging & Cognition”: Dortmund, Germany, April 25–27, 2013]
Doi
Link to details 980
Title Dependence of the geriatric depression on nutritional status and anthropometric indices in elderly population.
Abstract Objective: Malnutrition and depression are highly prevalent in the elderly and can lead to unfavorable outcomes. The aims of the current study were to determine the association between malnutrition and depression and also to find any correlation of depression with some anthropometric indices in free living elderly. Method: In this cross-sectional study, 337 elderly subjects (193 females) were selected using cluster sampling. Depressive symptoms and nutritional status were determined by the Geriatric Depression Scale (GDS) and the Mini-Nutritional Assessment (MNA) scores questionnaires, respectively. Anthropometric indices were measured all in standard situations. Chi squared test and t-test were used when necessary. Pearson correlation coefficients were calculated for linear relations between variables. Results: Of all the total subjects, 43.62 %were depressed; and of whom, 48.01% were malnourished or at risk of malnutrition. GDS had a significant negative dependence with the MNA for the entire sample (r=-0.58, p<0.0001). However, there was no significant correlation between age and GDS or MNA scores. Moreover, the mean GDS scores differed significantly between men and women (p <0.05), and women were more depressed than men (27.9% vs. 15%, respectively). The elderly subjects living in urban areas were more depressed than those living in rural areas (39.46% vs. 3.85% respectively). Conclusion: The results of the present study revealed a high prevalence of depression and malnutrition among old subjects. Moreover, depression was associated with worsening of nutritional status. The mechanism of this association needs further study.
Authors Ahmadi,S. M.;Mohammadi,M. R.;Mostafavi,S. -A;Keshavarzi,S.;kooshesh,S. -M -A;Joulaei,H.;Sarikhani,Y.;Peimani,P.;Heydari,S. T.;Lankarani,K. B.
Publication Year 2013
Journals Iran J Psychiatry.
Volume 8
Issue 2
Startpage 92-
Endpage 96
Doi
Link to details 981
Title Limited utility of adipokine levels in the diagnosis of malnutrition in the elderly.
Abstract BACKGROUND AND AIMS: Adipokine levels may have a role in the diagnostic and prognostic evaluation of malnutrition. The aim of the present study was to evaluate the correlation between malnutrition score and leptin, other biological markers, and body mass index (BMI) in the diagnosis of malnutrition in the elderly. METHODS: In this cross-sectional observational study, we enrolled subjects over 70 years. Exclusion criteria were diabetes mellitus, obvious thyroid disorders, significant edema, renal dysfunction, chronic liver disease, symptomatic cardiovascular diseases, and malignity. Patients' demographic and medical data were recorded and anthropometric measurements were performed. Laboratory parameters including leptin, IGF-1, IGFBP-3, IL-6, TNF-alpha were measured. We defined malnutrition according to mini nutritional assessment (MNA) scale. Patients were divided into four groups according to BMI quartiles. RESULTS: Average age of the patients was 81.9 +/- 4.8 years, 68.2 % female and 31.8 % male. According to their MNA scores, 103 (66.9 %) were well nourished, 33 (21.4 %) were under malnutrition risk and 18 (11.7 %) were malnourished. MNA total and screening scores were positively correlated with albumin, BMI, high-density lipoprotein cholesterol and estimated glomerular filtration rate. Serum leptin levels (ng/ml) were 18.9 +/- 22.6, 22.3 +/- 21.9, 51.9 +/- 85.5, and 61.7 +/- 56.1 in BMI groups 1-4, respectively. BMI was positively correlated with leptin and triglyceride levels. Leptin levels were similar among nutritional state groups. Neither BMI nor MNA scores had any significant correlation with adiponectin, ghrelin, IGF-1, or IGFBP-3. CONCLUSIONS: Adipokine levels do not seem to give relevant information in nutritional state assessment.
Authors Akin,S.;Tufan,F.;Bulut,L.;Genc,S.;Bahat,G.;Saka,B.;Erten,N.;Karan,M. A.
Publication Year 2013
Journals Aging Clin Exp Res.
Volume
Issue
Startpage Oct 22 [Published online]
Endpage
Doi doi:10.1007/s40520-013-0158-y
Link to details 982
Title The relationship between nutritional status, functional capacity, and health-related quality of life in older adults with type 2 diabetes: A pilot explanatory study.
Abstract Objective: To explore the relationship between nutritional status, functional capacity and health-related quality of life (HRQoL) in older adults with type 2 diabetes (T2DM). Design: Cross-sectional study. Setting and participants: Forty two non-insulin dependent older adults from a primary care center in Seville, Spain. Measurements: Function was assessed with a battery of standardized physical fitness tests. Nutritional status was assessed using the Mini Nutritional Assessment (MNA) and the European Quality of Life Questionnaire (EQ-5D-3L) was used to assess HRQoL. Results: There was an association between MNA-nutritional status and lower body strength as assessed by the chair sit-stand test (rho=.451; p=.037) and between MNA-nutritional status and EQ-5D-3L-HRQoL (EQ-5D-3Lutility, rho=.553; p<.001 and EQ-5D-3LVAS rho=.402; p<.001). An MNA item by item correlation analysis with HRQoL and lower limb strength demonstrated that HRQoL appears to be related to functional capacity (principally lower body strength, motor agility and cardiorespiratory fitness) among participants. These results were maintained when correlations were adjusted for co-morbidity. Conclusion: Our results demonstrated that nutritional status is moderately associated with HRQoL and lower limb strength in patients with T2DM. Our data suggest that more emphasis should be placed on interventions to encourage a correct diet and stress the needed to improve lower body strength to reinforce better mobility in T2DM population (copyright) 2013 Serdi and Springer-Verlag France.
Authors Alfonso-Rosa,R. M.;Del Pozo-Cruz,B.;Del Pozo-Cruz,J.;Del Pozo-Cruz,J. T.;Sanudo,B.
Publication Year 2013
Journals J Nutr Health Aging.
Volume 17
Issue 4
Startpage 315-
Endpage 321
Doi doi:10.1007/s12603-013-0028-5
Link to details 983
Title Comprehensive geriatric assessment in older patients with cancer: Two steps forward?
Abstract [Editorial, no abstract].
Authors Alibhai,S. M. H.
Publication Year 2013
Journals J Geriatr Oncol.
Volume 4
Issue 3
Startpage 205-
Endpage 207
Doi doi:10.1016/j.jgo.2013.04.009