MNA® Literature Database

Welcome to the MNA® Literature Database.  Here you will find valuable information on the extensive research that supports use of the MNA® in the elderly.  Currently there are more than 1100 published research articles that reference the MNA®.  Access links to abstracts of all MNA® articles and references cited on the website using the search function, e.g. select “Abstract” and enter a keyword to search abstracts.

Total Records Found: 1162, showing 10 per page
Link to details 1177
Title Micronutrients supplementation and nutritional status in cognitively impaired elderly persons: A two-month open label pilot study.
Abstract Background: Malnutrition is a widespread problem in elderly people and is associated with cognitive decline. However, interventional studies have produced ambiguous results. For this reason, we wanted to determine the effect of micronutrient supplementation on blood and tissue levels and on general nutritional status in persons with mild or moderate cognitive impairment. Methods. We performed a 2-month, open-label trial, administering a daily micronutrient supplement to 42 memory clinic patients with mild cognitive deficits. Blood levels of antioxidants, zinc, and B vitamins were determined before and after supplementation. In addition, we assessed metabolic markers for B vitamins and intracellular (buccal mucosa cell [BMC]) antioxidant levels. Nutritional status was assessed by using the Mini Nutritional Assessment (MNA). Results: Blood levels of B vitamins, folic acid, lutein, (beta)-Carotene, -Carotene, and -Tocopherol increased significantly. Decreases in homocysteine levels and the thiamine pyrophosphate effect and an increase in holotranscobalamin were observed. We found no increase in intracellular antioxidant levels of BMC. The MNA score in subjects at risk for malnutrition increased significantly, mainly owing to better perception of nutritional and overall health status. Conclusions: Micronutrient supplementation improved serum micronutrient status, with improved metabolic markers for B vitamins but not for intracellular antioxidant status, and was associated with improved self-perception of general health status. Our data underline the necessity of determining micronutrient status and support the use of additional assessments for general health and quality of life in nutritional supplementation trials. (copyright) 2013 von Arnim et al.; licensee BioMed Central Ltd.
Authors Von Arnim,C. A. F.;Dismar,S.;Ott-Renzer,C. S.;Noeth,N.;Ludolph,A. C.;Biesalski,H. K.
Publication Year 2013
Journals Nutr J.
Volume 12
Issue 1
Startpage 1-
Endpage 16
Doi doi:10.1186/1475-2891-12-148
Link to details 1178
Title Malnutrition is associated with poor rehabilitation outcome in elderly inpatients with hospital-associated deconditioning a prospective cohort study.
Abstract Objective: To investigate the association between nutritional status and rehabilitation outcome in elderly inpatients with hospital-associated deconditioning. Design: A prospective cohort study. Subjects/patients: One hundred sixty-nine consecutive elderly inpatients diagnosed with hospital-associated deconditioning. Methods: Nutritional status at referral was assessed by the Mini Nutritional Assessment Short Form at the University Medical Center. Body mass index, haemoglobin, albumin, total lymphocyte count, C-reactive protein, cause of malnutrition, and feeding route were also investigated. Primary outcome was Barthel Index score at discharge. Results: A total of 148 patients (87.6%) were malnourished, and 21 were at risk for malnutrition. There were no patients with normal nutritional status. Malnourished patients had a lower Barthel Index score at discharge than those at risk for malnutrition. Chronic disease-related malnutrition, oral intake, and parenteral nutrition were associated with the Barthel Index score at discharge. There were significant correlations between the Barthel Index score at discharge and nutritional score, albumin, and total lymphocyte count. In multiple regression analysis, Mini Nutritional Assessment Short Form, albumin, and chronic disease-related malnutrition were significantly associated with the Barthel Index score at discharge. Conclusion: Most elderly inpatients with hospital-associated deconditioning are malnourished. Nutritional status, albumin, and chronic disease-related malnutrition are associated with poor rehabilitation outcome in hospital-associated deconditioning.
Authors Wakabayashi,H.;Sashika,H.
Publication Year 2013
Journals J Rehabil Med.
Startpage Nov 8 [Epub ahead of print]
Doi doi:10.2340/16501977-1258
Link to details 1179
Title The short-form mini-nutritional assessment is as effective as the full-mini nutritional assessment in predicting follow-up 4-year mortality in elderly Taiwanese.
Abstract Objective: To compare the mortality-predictive ability of the full- and short-form (SF) Mini Nutritional Assessment (MNA). Design: A prospective cohort study. Setting: Population-representative sample. Participants: 2872 (greater-than or equal to)65-year old men and women. Measurements: The study analyzed 1999 and 2003 datasets of the Taiwan Longitudinal Survey on Aging (TLSA). Subjects were graded for nutritional status with the full-MNA and MNA-SF of a Taiwanese-specific version (T2, containing calf circumference instead of BMI) at baseline (1999) and tracked their survival status for 4 years. Mortality-predictive abilities of the full-MNA and MNA-SF were compared using Cox regression analysis and Net Reclassification Improvement (NRI). Results: The full-MNA and MNA-SF have comparable abilities in predicting follow-up 4-year mortality risk according to the hazard ratios (all p<0.001) and Akaike information criterion (AIC). It also showed a slight improvement (not significant) if the full-MNA in a predictive model was replaced by the MNA-SF (NRI=0.09%, p=0.956). Conclusion: The MNA-SF has at least comparable or even slightly better ability in predicting follow-up 4-year mortality risk of elderly Taiwanese. Results suggest that MNA-SF with calf circumference may possess some basic characteristics of a comprehensive and universal geriatric screening scale. (copyright) 2013 Serdi and Springer-Verlag France.
Authors Wang,J. Y.;Tsai,A. C.
Publication Year 2013
Journals J Nutr Health Aging.
Volume 17
Issue 7
Startpage 594-
Endpage 598
Doi doi:10.1007/s12603-013-0048-1
Link to details 1180
Title The prevalence of malnutrition in frail older veterans.
Abstract Background: Malnutrition presents serious risks to elders, and is a good predictor of morbidity and mortality, but validated screening tools remain underutilized. A nation-wide group of Department of Veterans Affairs' Home Based Primary Care (HBPC) programs participated in a multi-sited quality improvement (QI) process to evaluate the baseline nutritional status for patients enrolled in HBPC. The Mini Nutritional Assessment short form (MNA-SF), a screening tool that has been validated in multiple populations, was chosen as the standard. We present the initial findings of the group: the prevalence of malnutrition and risk of malnutrition among veterans in HBPC program. This is the first study to look at the prevalence of malnutrition among these frail, largely homebound elders. Methods: Local QI projects were initiated, using the MNA-SF, to determine presence of malnutrition and risk of malnutrition among patients from 18 HBPC programs across the country. Data was collected between April and September, 2012. Each site provided data in de-identified, aggregate form to a coordinating dietitian (CC). Due to the limited nature of the QI data, unadjusted prevalence was calculated for the entire sample size and for each site. Results: Over a six month period, 2,252 veterans over the age of 65 were assessed using the MNA-SF. Of these, 909 (40.3%) of veterans were found to be at risk for malnutrition, and 344 (15%) were discovered to be malnourished. The overall prevalence rate was 55.6% for both malnutrition and nullat risknull for malnutrition. Conclusions: In this group of frail elders, the majority were either at risk of malnutrition or already malnourished. This finding underscores the need to identify patients at nutritional risk using validated tools in order to target timely interventions. Improved nutritional status can lead to improved quality of life and better clinical outcomes for patients. The data from this study provides baseline characterization of this population and serves as a rationale for the development of interventions, including the adoption of the MNA-SF as a standard screening tool for HBPC programs nationwide.
Authors Win,A. Z.;Ceresa,C.;Allison,T. A.
Publication Year 2013
Journals J Am Geriatr Soc.
Volume 61
Issue 1
Startpage S159
Endpage [Abstract, American Geriatrics Society 2013 Annual Scientific Meeting, Grapevine, TX, May 2-5, 2013]
Doi doi:10.1111/jgs.12263
Link to details 1181
Title Nutrition screening of older people in a community general practice, using the MNA-SF.
Abstract Background: Objective: The study aimed to determine the prevalence of malnutrition risk in a population of older people (aged 75 years and over) attending a community general practice and identify characteristics of those classified as malnourished or at risk of malnutrition. Design: Cross-sectional study of nutritional risk screen conducted over a six month period. Participants and setting: Patients attending a general practice clinic in Victoria, Australia, who attended for the "75 plus" health assessment check. Measurements: The Mini Nutritional Assessment Short Form (MNA(registered trademark)-SF) was included as part of the health assessment. Information was collected on living situation, co-morbidities, independence with meal preparation and eating, number of medications. Height and weight was measured and MNA(registered trademark)-SF score recorded. Results: Two hundred and twenty five patients attending a general practice for a health assessment with a mean age of 81.3(4.3)(SD) years, 52% female and 34% living alone. Only one patient was categorised by the MNA(registered trademark)-SF as malnourished, with an additional 16% classified as at risk of malnutrition. The mean Body Mass Index (BMI) of the at-risk group was significantly lower than the well-nourished group (23.6 (plus or minus) 0.8 (SEM) vs 27.4 (plus or minus) 0.3; p=0.0001). However, 34% of the at-risk group had a BMI of 25 or more with only 13% in the underweight category. Conclusion: In this population of older adults attending their general practitioner for an annual health assessment, one in six were identified as being at nutritional risk which is an additional risk factor for a severe health issue. Importantly, one third of the at-risk group had a BMI in the overweight or obese category, highlighting that older people can be at nutritional risk although they may be overweight or obese. (copyright) 2013 Serdi and Springer-Verlag France.
Authors Winter,J.;Flanagan,D.;McNaughton,S. A.;Nowson,C.
Publication Year 2013
Journals J Nutr Health Aging.
Volume 17
Issue 4
Startpage 322-
Endpage 325
Doi doi:10.1007/s12603-013-0020-0
Link to details 1182
Title The moderating effect of nutritional status on depressive symptoms in veteran elders with dementia: A spaced retrieval combined with Montessori-based activities.
Abstract AIM: To examine the long-term effects of fixed/individualized spaced retrieval combined with Montessori-based activities on nutritional status and body mass index and nutritional improvement's moderating effect on depressive symptoms for people with dementia during a specific follow-up period. BACKGROUND: The decrease in food intake, often combined with poor nutrition, may induce depressive symptoms in people with dementia. DESIGN: A single-blind, quasi-experimental study with repeated measures. METHODS: Twenty-five fixed group participants received spaced retrieval combined with Montessori-based activities over 24 sessions. Thirty-eight individualized group participants received the same intervention with different sessions, which was adjusted according to each participant's learning response. Twenty-seven control group participants just received routine care. The Chinese version of the Mini-Nutritional Assessment and Cornell Scale for Depression in Dementia scores and body mass index were recorded at pre-test, posttest and 1-, 3- and 6-month follow-ups. Data were collected between July 2008-February 2010. RESULTS: The Mini-Nutritional Assessment scores and body mass index of the fixed and individualized groups could be significantly increased over time. Additionally, the Cornell Scale for Depression in Dementia scores could be significantly reduced as a result of the improvement of the Mini-Nutritional Assessment scores arising from the individualized intervention. CONCLUSION: The depressive symptoms of residents with dementia could be moderated by the individualized intervention through nutritional improvement. Trained clinical nurse specialists can use this individualized intervention for residents with dementia who also have poor nutrition and depressive symptoms.
Authors Wu,H. S.;Lin,L. C.
Publication Year 2013
Journals J Adv Nurs.
Volume 69
Issue 10
Startpage 2229-
Endpage 2241
Doi doi:10.1111/jan.12097
Link to details 1183
Title Establishment of a short-form screening test for malnutrition in a newly developed comprehensive geriatric assessment initiative named 'Dr. SUPERMAN'. [Article in Japanese].
Abstract AIM: Assessment of the nutritional state is important in comprehensive geriatric assessment (CGA). Several standardized screening tests for malnutrition are available such as the Mini-Nutritional Assessment (MNA) and MNA-Short Form (MNA-SF). However, it takes more than 10 minutes to perform the MNA-SF alone. We have developed a CGA initiative named 'Dr. SUPERMAN', which is designed to accomplish CGA within 10 minutes. In this study, we evaluated a short-form screening test for malnutrition preceding the MNA. METHODS: The MNA-SF, which consists of 6 items (A-F), was administered to 163 elderly outpatients (mean age: 83.4 years, 80 men) with various diseases. Using the results of the MNA-SF score (normal >/= 12 and abnormal /= 23/CC <31 cm along with a positive wall-occiput test was a useful and valuable SF screening test for malnutrition in elderly outpatients.
Authors Yamakawa,H.;Ohnuma,T.;Satoh,T.;Sugiyama,K.;Harikae,M.;Iwamoto,T.
Publication Year 2013
Journals Nihon Ronen Igakkai Zasshi.
Volume 50
Issue 2
Startpage 233-
Endpage 242
Link to details 1184
Title Mini nutritional assessment as a useful method of predicting the development of pressure ulcers in elderly inpatients.
Abstract Objectives To determine the usefulness of the Mini Nutritional Assessment (MNA) and plasma amino acid analysis in predicting the formation of pressure ulcers (PUs) in inpatients. Design Prospective, observational cohort study with a mean observation period of 62.2 (plus or minus) 86.4 days. Setting Intermediate and acute care wards of a hospital in rural Japan. Participants Inpatients with an average age of 85.0 (plus or minus) 7.6 (N = 422). Measurements Mini Nutritional Assessment, Subjective Global Assessment (SGA), Braden Scale (PU prognostic score), PU formation, and biochemical analysis including plasma amino acid concentrations. Results PUs developed in 7.1% of participants. A MNA score of less than 8 was more sensitive than a rating of moderate or severe malnourishment on the SGA combined with a Braden Scale score of less than 15 in predicting future PUs. The area under the receiver operating characteristic curve (AUC) of the MNA was superior to that of the Braden Scale. The Braden Scale nutrition subscore had the lowest AUC of the six Braden Scale subscores. Individuals who developed PUs had significantly lower plasma arginine concentrations than those who did not. Conclusion Mini Nutritional Assessment was able to predict the development of PUs. A MNA score of less than 8 performed better than the SGA, Braden Scale, and plasma arginine levels in predicting PU development. Although lower plasma arginine concentration at time of admission was associated with PU development, the AUC for arginine was not significantly different from 0.50. The findings from this prospective study support the use of nutritional assessment in inpatients to predict PU risk and target appropriate interventions. (copyright) 2013, The American Geriatrics Society.
Authors Yatabe,M. S.;Taguchi,F.;Ishida,I.;Sato,A.;Kameda,T.;Ueno,S.;Takano,K.;Watanabe,T.;Sanada,H.;Yatabe,J.
Publication Year 2013
Journals J Am Geriatr Soc.
Volume 61
Issue 10
Startpage 1698-
Endpage 1704
Doi doi:10.1111/jgs.12455
Link to details 1185
Title Relationship between depression and risk of malnutrition among community-dwelling young-old and old-old elderly people.
Abstract This study explores the association between nutritional status and depression among healthy community-dwelling young-old (aged 65-74) and old-old elderly (aged 75 and older). A cross-sectional design was implemented. A total of 274 community-dwelling older individuals (142 young-old; 132 old-old) were assessed using the Geriatric Depression Scale (GDS), Mini-Nutritional Assessment Short-Form (MNA-SF) and Life-Space Assessment. Logistic regression analysis was used to determine if depression was independently associated with risk of malnutrition, stratified by age (young-old vs. old-old). In the logistic regression model for young-old, being at risk of malnutrition (MNA-SF ((less-than over equal to)11) was strongly associated with depression (GDS ((greater-than over equal to)5;) (likelihood ratio (nu) = 6.26; 95% confidence interval [CI]: 1.91-20.49). In contrast, in the old-old group, the model was not statistically significant. Depression and nutritional status were strongly correlated in young-old but not in old-old community-dwelling elderly. This study reveals that not only the factors correlated with but also the symptoms of depression may vary among different age stratifications of the elderly.
Authors Yoshimura,K.;Yamada,M.;Kajiwara,Y.;Nishiguchi,S.;Aoyama,T.
Publication Year 2013
Journals Aging Ment Health.
Volume 17
Issue 4
Startpage 456-
Endpage 460
Doi doi:10.1080/13607863.2012.743961
Link to details 1186
Title Prevalencia de desnutricion en afectados de esclerosis multiple que reciben tratamiento rehabilitador en los hospitales de dia de la Fundacio Esclerosi Multiple. [Prevalence of malnutrition in affected multiple sclerosis receiving rehabilitation trea
Abstract Introduction Malnutrition is currently a serious problem which can lead to significant clinic and economic consequences. There is little in the literature on malnutrition in Multiple Sclerosis (MS) is largely related to the presence of dysphagia, and contemplates its appearance in very advanced stages of the disease. General objective To determine the prevalence of malnutrition in MS patients having neuro-rehabilitation treatment in the day hospital of the Fundacion Esclerosis Multiple. Specific objective To determine how many patients affected by malnutrition receive a specific nutritional treatment Method Based on an observational, cross-sectional and descriptive study, a sample of 150 MS patients was selected. Demographic and clinic data, as well as a malnutrition Scale, were collected from each patient Results In the study, 20.4% had a satisfactory nutritional condition, 69.3% had a threat of malnutrition, and 10.3% were malnourished. Nutritional intervention was performed in 71.42% of the malnourished patients. According to the MNA scale, of all malnourished patients: 28.58% did not receive any treatment, 35.71% have a nutritional supplement, and 35.71% receive dietary advice. Conclusions Malnutrition is a major problem in MS patients, as only 20.4% of the sample had a satisfactory nutritional status. It seems that there may be a relationship between the degree of disability and the occurrence of this problem, in patients with low levels of disabilities there are no cases of malnutrition. If we take into account the symptom of dysphagia observed in 76.92% of patients without dysphagia are at risk of malnutrition or are malnourished. This fact opens the door to look for other symptoms or situations that have a negative impact on health status. (copyright) 2013 Sociedad Espanola de Enfermeria Neurologica. Publicado por Elsevier Espana, S.L. Todos los derechos reservados.
Authors Zabay Neiro,C.;Sanchez Pous,S.;Casalilla Puertolas,M.
Publication Year 2013
Journals Rev Cient Soc Esp Enferm Neurol.
Volume 38
Issue 1
Startpage 42-
Endpage 47
Doi doi:10.1016/j.sedene.2013.06.001