MNA® Literature Database

Welcome to the MNA® Literature Database.  Here you will find valuable information on the extensive research that supports use of the MNA® in the elderly.  Currently there are more than 1100 published research articles that reference the MNA®.  Access links to abstracts of all MNA® articles and references cited on the website using the search function, e.g. select “Abstract” and enter a keyword to search abstracts.

Total Records Found: 1162, showing 10 per page
Link to details 1041
Title Association of the oral health impact profile with malnutrition risk in Spanish elders.
Abstract The objective of this study was to determine any relationship between oral health-related quality of life (OHR-QoL) and malnutrition risk in the elderly using the oral health impact profile (OHIP). We studied 250 institutionalized elderly people, 162 females and 88 males, with and without teeth. Data were gathered on: general health; oral health; malnutrition risk, measured with the Mini Nutritional Assessment (MNA); and OHR-QoL, evaluated with the OHIP. A multivariate binary logistic regression model was constructed with malnutrition presence/risk as dependent variable. Mean age was 82.7 (plus or minus) 8.2 years. Malnutrition or malnutrition risk was shown by 36.8% of the sample. OHIP was associated with malnutrition/risk after adjustment for age, sex, functional status, and mild dementia diagnosis. Malnutrition/risk was 3.43-fold more likely in participants with OHIP-reported "problems" than in those with none. The conclusion of the study was that OHIP-measured OHR-QoL is associated with malnutrition risk. (copyright) 2013 Elsevier Ireland Ltd.
Authors Gil-Montoya,J. A.;Ponce,G.;Sanchez Lara,I.;Barrios,R.;Llodra,J. C.;Bravo,M.
Publication Year 2013
Journals Arch Gerontol Geriatr.
Volume 57
Issue 3
Startpage 398-
Endpage 402
Doi doi:10.1016/j.archger.2013.05.002
Link to details 1040
Title Malnutrition: A highly predictive risk factor of short-term mortality in elderly presenting to the emergency department.
Abstract Objectives: To identify independent risk factors of mortality among elderly patients in the 3 months after their visit (T3) to an emergency department (ED). Design: Prospective cohort study. Setting: University hospital ED in an urban setting in France. Participants: One hundred seventy-three patients aged 75 and older were admitted to the ED over two weeks (18.7% of the 924 ED visits). Of these, 164 patients (94.8%) were included in our study, and 157 (95.7%) of them were followed three months after their ED visit. Measurements: During the inclusion period (T0), a standardized questionnaire was used to collect data on socio-demographic and environmental characteristics, ED visit circumstances, medical conditions and geriatric assessment including functional and nutritional status. Three months after the ED visits (T3), patients or their caregivers were interviewed to collect data on vital status, and ED return or hospitalization. Results: Among the 157 patients followed at T3, 14.6% had died, 19.9% had repeated ED visits, and 63.1% had been hospitalized. The two independent predictive factors for mortality within the 3 months after ED visit were: malnutrition screened by the Mini Nutritional Assessment short-form (MNA-SF) (OR=20.2; 95% CI: 5.74-71.35; p<.001) and the Cumulative Illness Rating Scale for Geriatrics (CIRS-G) score (OR=1.1; 95% CI: 1.01-1.22; p=.024). Conclusion: Malnutrition is the strongest independent risk factor predicting short-term mortality in elderly patients visiting the ED, and it was easily detected by MNA-SF and supported from the ED visit. (copyright) 2013 Serdi and Springer-Verlag France.
Authors Gentile,S.;Lacroix,O.;Durand,A. C.;Cretel,E.;Alazia,M.;Sambuc,R.;Bonin-Guillaume,S.
Publication Year 2013
Journals J Nutr Health Aging.
Volume 17
Issue 4
Startpage 290-
Endpage 294
Doi doi:10.1007/s12603-012-0398-0
Link to details 1039
Title Interrelationship of oral health status, swallowing function, nutritional status, and cognitive ability with activities of daily living in Japanese elderly people receiving home care services due to physical disabilities.
Abstract Objectives: Malnutrition and cognitive impairment lead to declines in activities of daily living (ADL). Nutritional status and cognitive ability have been shown to correlate with oral health status and swallowing function. However, the complex relationship among the factors that affect decline in ADL is not understood. We examined direct and indirect relationships among oral health status, swallowing function, nutritional status, cognitive ability, and ADL in Japanese elderly people living at home and receiving home care services because of physical disabilities. Methods: Participants were 286 subjects aged 60 years and older (mean age, 84.5 (plus or minus) 7.9 years) living at home and receiving home care services. Oral health status (the number of teeth and wearing dentures) was assessed, and swallowing function was examined using cervical auscultation. Additionally, ADL, cognitive ability, and nutritional status were assessed using the Barthel Index, the Clinical Dementia Rating Scale, and the Mini Nutritional Assessment-Short Form, respectively. Path analysis was used to test pathways from these factors to ADL. Results: The mean number of teeth present in the participants was 8.6 (plus or minus) 9.9 (edentates, 40.6%). Dysphagia, malnutrition, and severe cognitive impairment were found in 31.1%, 14.0%, and 21.3% of the participants, respectively. Path analysis indicated that poor oral health status and cognitive impairment had a direct effect on denture wearing, and the consequent dysphagia, in addition to cognitive impairment, was positively associated with malnutrition. Malnutrition as well as dysphagia and cognitive impairment directly limited ADL. Conclusions: A lower number of teeth are positively related to swallowing dysfunction, whereas denture wearing contributes to recovery of swallowing function. Dysphagia, cognitive impairment, and malnutrition directly and indirectly decreased ADL in elderly people living at home and receiving home nursing care. The findings suggest that preventing tooth loss and encouraging denture wearing when teeth are lost may indirectly contribute to maintaining or improving ADL, mediated by recovery of swallowing function and nutritional status. (copyright) 2012 John Wiley & Sons A/S.
Authors Furuta,M.;Komiya-Nonaka,M.;Akifusa,S.;Shimazaki,Y.;Adachi,M.;Kinoshita,T.;Kikutani,T.;Yamashita,Y.
Publication Year 2013
Journals Community Dent Oral Epidemiol.
Volume 41
Issue 2
Startpage 173-
Endpage 181
Doi doi:10.1111/cdoe.12000
Link to details 1038
Title Leg edema detected on comprehensive geriatric assessment for elderly outpatients and its associated risk factors.
Abstract AIM: Leg edema, observed on comprehensive geriatric assessment (CGA) of 142 elderly outpatients with a variety of chronic diseases, was studied clinically to clarify its incidence and its associated risk factors. METHODS: The severity of pitting edema was assessed at 3 points, namely, the pretibial edge, medial malleolus, and the dorsum of the foot. On palpation, edema was graded as 0 to 3 for each point on one leg, the sum of which was used as the edema score. According to the edema score, subjects were divided into 3 groups; the moderate to severe (MS) group, the slight to mild (SM) group, and the group without pitting edema. The MS group was defined as having an edema score of 4 or more or edema of grade 2 or more, while the SM group was defined as having an edema score of 2 to 3 points without edema of grade 2 or more. The status of underlying disease, vascular risks, varicose veins, medications, daily activity, nutrition, total protein (TP), albumin, brain natriuretic peptide (BNP), and the estimated glomerular filtration rate (eGFR) were compared among the 3 groups. RESULTS: There were 36 subjects in the MS group and 19 subjects in the SM group. Diabetes, atrial fibrillation, varicose veins, and polypharmacy were more frequent in the MS group than in the control group. Sedentary life style, house-bound, and gait trouble were significantly more frequent in the MS and SM groups. There were no significant differences in the scores of the Mini-Nutritional Assessment Short Form among the groups, although both the body weight and calf circumference in the MS group were significantly greater than those in the group without pitting edema. Low serum TP, albumin and eGFR were seen in the MS group as well as high BNP levels. Multiple regression analysis revealed diabetes, varicose veins, sedentarism, and hypoalbuminemia as risk factors associated with leg edema (R(2)=0.365, p<0.0001). CONCLUSION: Leg edema was frequent in the elderly outpatients and was associated strongly with diabetes, varicose veins, sedentarism, and hypoalbuminemia. These findings suggest that advising against a sedentary life style could help the resolution of edema, and also indicates the clinical usefulness of CGA. Furthermore, leg edema should be seriously considered along with nutritional assessment because edema could influence various anthropometric parameters.
Authors Fukazawa,R.;Koyama,S.;Kanetaka,H.;Umahara,T.;Hanyu,H.;Iwamoto,T.
Publication Year 2013
Journals Nihon Ronen Igakkai Zasshi.
Volume 50
Issue 3
Startpage 384-
Endpage 391
Doi doi:10.3143/geriatrics.50.384
Link to details 1037
Title Effect of postoperative delirium on quality of life and daily activities 6 month after elective cardiac surgery in the elderly.
Abstract Objectives: Delirium after surgery is known to have an influence on mortality, length of hospital stay and nursing home placement. Especially elderly patients are concerned about losing independence or ending up in a care facility. The aim of the study was to examine the influence of postoperative delirium on quality of life (QOL) and daily activities six month after cardiac surgery in elderly patients. Methods: 183 patients (greater-than or equal to)70 years undergoing elective coronary artery bypass and/or valve surgery between December 2010 and February 2012 were involved in this prospective study. Delirium was validated by Confusion Assessment Method for the ICU (CAM-ICU). The following tests were performed six months after surgery: Activities of Daily Living (IADL), Barthel index, Nuremberg Age Activity List (NAA), quality of life (SF-12: physical and mental component score; PCS/MCS), Minimal Nutritional Assessment (MNA) and Geriatric Depression Scale (GDS). The effect of postoperative delirium was measured by analysis of covariance. Results: Sixty patients (32.8%) developed a delirium. These patients had lower QOL concerning PCS (delirium 39.0 vs. no delirium 43.3; p = 0.009), and MCS (delirium 48.8 vs. no delirium 52.4; p = 0.02). Patients who had no delirium postoperatively showed higher levels of activity of daily living: Barthel index (99.1 vs. 94.0; p = 0.001), IADL (6.8 vs. 6.2; p = 0.036), NAA (26.9 vs. 29.3; p = 0.016). Patients with delirium had a lower level of nutrition (MNA: 25.3 vs. 26.4; p = 0.03). There were no differences between groups with regard to depression (GDS: with delirium 2.9 vs. 2.5 without delirium; p = 0.339). Conclusions: Postoperative delirium seems to have a negative effect on quality of life and level of daily activities six month after cardiac surgery in the elderly. Prevention of postoperative delirium may ameliorate the quality of live after surgery. Further studies are needed to confirm these data.
Authors Freibrodt,J.;Huppe,M.;Sedemund-Adib,B.;Sievers,H. H.;Schmidtke,C.
Publication Year 2013
Journals Thorac Cardiovasc Surg.
Volume 61
Issue 1
Endpage Abstract, 42nd Annual Meeting of the German Society for Cardiovascular and Thoracic Surgery, Freiburg, Germany, February 17-20, 2013]
Doi doi:10.1055/s-0032-1332732
Link to details 1036
Title Utility of geriatric assessment to predict mortality in the oldest old: The OCTABAIX study 3-year follow-up.
Abstract Objective: Few studies have prospectively evaluated the utility of geriatric assessment tools as predictors of mortality in the oldest population. We investigated predictors of death in an oldest-old cohort after 3 years of follow-up. Methods: The Octabaix study is a prospective, community-based study with a follow-up period of 3 years involving 328 subjects aged 85 at baseline. Data were collected on functional and cognitive status, co-morbidity, nutritional and falls risk, quality of life, social risk, and long-term drug prescription. Vital status for the total cohort was evaluated after 3 years of follow-up. Results: Mortality after 3 years was 17.3%. Patients who did not survive had significantly poorer baseline functional status for basic and instrumental activities of daily living (Barthel and Lawton Index), higher co-morbidity (Charlson), higher nutritional risk (Mini Nutritional Assessment), higher risk of falls (Tinetti Gait Scale), poor quality of life (visual analog scale of the Quality of Life Test), and higher number of chronic drugs prescribed. Cox regression analysis identified the Lawton Index (hazard ratio [HR] 0.82, 95% confidence interval [CI] 0.73-0.89) and the number of chronic drugs prescribed (HR 1.09, 95% CI 1.01-1.18) as independent predictors of mortality at 3 years. Conclusions: Among the variables studied, the ability to perform instrumental activities of daily living and using few drugs on a chronic basis at baseline are the best predictors of which oldest-old community-dwelling subjects survive after a 3-year follow-up period. (copyright) Mary Ann Liebert, Inc.
Authors Formiga,F.;Ferrer,A.;Chivite,D.;Montero,A.;Sanz,H.;Pujol,R.;Almeda,J.;Badia,T.;Lobato,A.;Fernandez,C.;Ferrer,A.;Formiga,F.;Gil,A.;Megido,M. J.;Padros,G.;Sarro,M.;Tobella,A.
Publication Year 2013
Journals Rejuvenation Res.
Volume 16
Issue 4
Startpage 279-
Endpage 284
Doi doi:10.1089/rej.2013.1422
Link to details 1035
Title Nutritional intervention in patients with advanced dementia in a psychogeriatrics unit.
Abstract Objective.- To establish the importance of nutritional intervention in patients with advanced dementia. Material and methods.- Assess the effectiveness of specific nutritional intervention, in 8 patients with advanced dementia (100% women, FAST 7e), age (88(plus or minus)9.39 years) and total dependence to ADL MBI 1(plus or minus)1.98 points) after six months of treatment, through the MNA-SF and biochemical markers of malnutrition. Results.- In October 2012, our patient's BMI was 19.11(plus or minus)2.99 points, and the score of the MNA-SF was 7.75(plus or minus)1.29 points, with a prevalence of malnutrition of 62.5%. Note that there is dysphagia (Bedside method) in 62.5% of the patients. After six months of intervention (adapted basic nutrition (diet mixer and hydration with liquids gelatinized or thickened in texture honey (n = 3) and nectar (n = 2) and supplementation with highprotein and high-calorie product and calcifediol), is objectively a gain of 7.2(plus or minus)1.46 kg (BMI 22.21(plus or minus)3.04). After the intervention, the prevalence of malnutrition is 12.5% (MNA-SF 8.88(plus or minus)1.05). Furthermore, we obtained a standardization of analytical parameters of malnutrition such as albumin (3.77(plus or minus)0.24), lymphocytes (1780(plus or minus)185.40), total proteins (6.5(plus or minus)0.36), total cholesterol (208(plus or minus)33.67), transferrin (245.25(plus or minus)22.88) and vitamin D (22.87(plus or minus)9). Conclusions.- Nutrition intervention in patients with advanced dementia decreases the prevalence of malnutrition and improves analytical parameters, minimizing the possibility of problems related to a poor nutritional status.
Authors Fernandez,N.;Martinez,V.;Aurre,I.;Sierra-Sesumaga,I.;Zalduegi,G.;Artaza,I.
Publication Year 2013
Journals Eur Geriatr Med.
Volume 4
Issue 1
Startpage S132
Endpage [Poster P369, 9th Congress of the European Union Geriatric Medicine Society (EUGMS), Venice, Italy, October 2-4, 2013]
Doi doi:10.1016/j.eurger.2013.07.433
Link to details 1034
Title Adequacy of food consumption and nutritional intake of dependent patients in a home care program.
Abstract Background and Objectives: Malnutrition in dependent patients has a high prevalence and it can decrease the quality of life and increase morbidity and mortality. The aim of this study is to describe the food consumption of dependent patients in a home care program and to analyze their nutrient intake adequacy. Methods: Cross-sectional study carried out in 10 Primary Care Centers of the Reus-Tarragona area. The patients of the Home Care Program were included when they had a score between 17-23.5 in the Mini Nutritional Assessment test (MNA), older than 65 and had caregivers. Food consumption was recorded by a food frequency questionnaire. The SPSS/PC program was used for statistical analysis. Results: 192 patients of the Home Care Program participated with a mean age of 85(plus or minus)7.2 years. The average intake of energy was 1801.5(plus or minus)434.3 kcal/day in men and 1694.86(plus or minus)312.1 kcal/day in women, 75.06% and 90.39% respectively of the Spanish recommended nutrient intake (RNI). The macronutrient distribution is 38.1% carbohydrates, 47.9% lipids and 13% proteins. The protein intake covers 86.4% of the RNI. The mean intakes of vitamin B3, vitamin B6, vitamin D, Ca and Fe are below two-thirds of the RNI. However, the probability of inadequate intake of vitamin B12 (3.15) and vitamin C (16.98) are low. Conclusions: Dependent patients had a diet high in fat and low in carbohydrates. The average intake of energy and proteins was adequate, but the main vitamins and minerals were below of the recommendations, except for vitamin B12 and vitamin C.
Authors Fernandez-Barres,S.;Marti,N.;Armengol,T. C.;Anguera,C.;Castelao-Alvarez,A. I.;Martinez-Blesa,T.;Pedret,R.;Basora,J.;Arija,V.
Publication Year 2013
Journals Ann Nutr Metab.
Volume 62
Issue 2
Startpage 74
Endpage [Poster P146, Mediterranean Foods on Health and Disease, World Forum for Nutrition Research Conference, Reus, Spain, May 20-21, 2013]
Doi doi:10.1159/000351281
Link to details 1033
Title Motor and non-motor determinants of chronic fatigue in idiopathic Parkinson's disease (IPD).
Abstract Background: Fatigue is one of themost common non-motor symptoms in patients with Parkinson's disease(PD) with significant impact on quality of life. Fatigue has received increasing attention during recent decade; however, few studies have examined the determinant factors of fatigue and little is known about the relationship between fatigue and other motor and non-motor symptoms. Objective: The aims of this study were to evaluate determinant factors relating to fatigue in PD and to compare the strength of measure of association for different non-motor and motor symptoms with fatigue severity. Patients and methods: This cross-sectional study was performed in a movement disorder clinic in Tehran, Iran during 2011-2012. A total number of 54 PD (38 males and 16 females) patients with the mean age of 62.5 (SD=9.1) yr were recruited. Fatigue was scored using the Fatigue Severity Scale (FSS). Other scales were used including PDQ39 (PD-specific QoL), HADS (anxiety & depression), MNA (mininutritional assessment), Schwab & England (activity of daily living) and Hoehn & Yahr scales (level of disability). Results: Patients' score in fatigue had significant correlation with anxiety (r=0.32, P=0.020), depression (r=0.41, P=0.002), disease severity measured by Hoehn & Yahr scale (r=0.36, P=0.007) and activity of daily living described by Schwab & England scale (r= -0.35, P=0.011). Conclusion: Our findings showed that more severe depression is accompanied with more severe fatigue in PD patients. In addition to motor symptoms of PD, anxiety and depression have noticeable relationship with fatigue, which must be considered in management of fatigue in PD patients.
Authors Fereshtehnejad,S. -M;Shafiei Sabet,M.;Farhadi,F.;Hadizadeh,H.;Khaefpanah,D.;Naderi,N.;Rahmani,A.;Delbari,A.;Shahidi,G. A.;Lokk,J.
Publication Year 2013
Journals J Neurol Sci.
Volume 333
Issue 1
Startpage e82
Endpage [Abstract No: 2457, Abstracts of the XXI World Congress of Neurology, Vienna, Austria, Sept 21-26, 2013]
Doi doi:10.1016/j.jns.2013.07.560
Link to details 1021
Title Agreement between different versions of MNA.
Abstract Malnutrition occurs frequently in the elderly with important clinical and functional consequences. Moreover, the treatment of malnutrition in the elderly may be effective if clinical and nutritional interventions are performed in the early stages. Therefore the early identification of the risk of malnutrition using validated and handy tools plays a pivotal role in terms of clinical outcome. Mini Nutritional Assessment (MNA) was validated for this purpose since many years but it is still ongoing the debate over whether the use of different items in certain clinical conditions can be effective without affecting the validity of the nutritional status evaluation. The aim of this study was to assess the agreement between different versions of MNA in the evaluation of nutritional risk in elderly subjects. Methods: 522 subjects, 345 women and 177 men, were recruited from nursing homes or were free living in three different regions in Italy. All subjects underwent a multidimensional geriatric evaluation, addressed especially to nutritional status. We compared three different versions of MNA: the "original" version; a "proportional" MNA (MNA-P) in which the total MNA score was replaced by the ratio between the maximum score that each subject could obtain without including the body mass index (BMI) and the total original MNA score; and a third version in which calf circumference (CC) and mid-upper arm circumference (MAC) were used instead of BMI. Results: According to the original MNA, a high prevalence of malnutrition was found out in both genders (26% of women and 16.3% of men); both the versions of MNA, in which BMI was not considered, showed a good predictive value compared to original MNA. In particular, the MNA-P. showed an overall efficiency equal to 89,1% with specificity and positive predictive value respectively equal to 97.5% and 95.2%. MNA-CC-MAC showed even better results in terms of overall efficiency (91.4%), sensitivity (81.1%), specificity (97.1%), positive and negative predictive values (94.2% and 94.4%, respectively). Conclusion: The different versions of MNA gave similar results in the classifications of subjects and in comparison with nutritional and biochemical parameters. Moreover MNA versions that did not considered BMI seem to be more effective in singling out subjects with risk factors related to malnutrition (disability, reduced strength and calf circumference, anaemia). (copyright) 2013 Serdi and Springer-Verlag France.
Authors Donini,L. M.;Poggiogalle,E.;Morrone,A.;Scardella,P.;Piombo,L.;Neri,B.;Cava,E.;Cucinotta,D.;Barbagallo,M.;Pinto,A.
Publication Year 2013
Journals J Nutr Health Aging.
Volume 17
Issue 4
Startpage 332-
Endpage 338
Doi doi:10.1007/s12603-013-0005-z