MNA® Literature Database

Welcome to the MNA® Literature Database.  Here you will find valuable information on the extensive research that supports use of the MNA® in the elderly.  Currently there are more than 1100 published research articles that reference the MNA®.  Access links to abstracts of all MNA® articles and references cited on the website using the search function, e.g. select “Abstract” and enter a keyword to search abstracts.

Total Records Found: 1162, showing 10 per page
Link to details 1188
Title Justificacion y diseno del estudio PICNIC: Programa de IntervenCion Nutricional en pacientes hospitalizados por Insuficiencia Cardiaca desnutridos. [Rationale and design of PICNIC study: Nutritional intervention program in hospitalized patients with
Abstract Introduction and objectives: Hospitalized patients with heart failure who are malnourished present a worse prognosis than those with an adequate nutritional status. It is unknown whether a nutritional intervention can modify the prognosis of these patients. The aim of this study is to assess the efficacy of a nutritional intervention on morbidity and mortality in hospitalized patients with heart failure who are malnourished. Methods: PICNIC is a multicentre, randomized, controlled trial in which hospitalized patients with heart failure and malnutrition, as defined by the Mini Nutritional Assessment, are randomly assigned to conventional management of heart failure or conventional management of heart failure and an individualized nutritional intervention consisting of 3 points: optimization of diet, specific recommendations, and prescription, if deemed necessary, of nutritional supplements. A sample size of 182 patients for a maximum follow-up of 12 months has been estimated. The primary endpoint is time to death from any cause or rehospitalization because of heart failure. Analysis is by intention to treat. Conclusions: PICNIC study will determine the prognostic impact of a nutritional intervention in hospitalized patients with heart failure who are malnourished. Full English text available from: (copyright) 2014 Sociedad Espanola de Cardiologia.
Authors Gamez-Lopez,A. L.;Bonilla-Palomas,J. L.;Anguita-Sanchez,M.;Moreno-Conde,M.;Lopez-Ibanez,C.;Alhambra-Exposito,R.;Castillo-Dominguez,J. C.;Villar-Raez,A.;Suarez de Lezo,J.
Publication Year 2014
Journals Rev Esp Cardiol.
Startpage Nov 19 [Epub ahead of print]
Doi doi:10.1016/j.recesp.2013.07.014; 10.1016/j.recesp.2013.07.014
Link to details 1189
Title Health status of UK care home residents: a cohort study.
Abstract BACKGROUND: UK care home residents are often poorly served by existing healthcare arrangements. Published descriptions of residents' health status have been limited by lack of detail and use of data derived from surveys drawn from social, rather than health, care records. AIM: to describe in detail the health status and healthcare resource use of UK care home residentsDesign and setting: a 180-day longitudinal cohort study of 227 residents across 11 UK care homes, 5 nursing and 6 residential, selected to be representative for nursing/residential status and dementia registration.Method: Barthel index (BI), Mini-mental state examination (MMSE), Neuropsychiatric index (NPI), Mini-nutritional index (MNA), EuroQoL-5D (EQ-5D), 12-item General Health Questionnaire (GHQ-12), diagnoses and medications were recorded at baseline and BI, NPI, GHQ-12 and EQ-5D at follow-up after 180 days. National Health Service (NHS) resource use data were collected from databases of local healthcare providers. RESULTS: out of a total of 323, 227 residents were recruited. The median BI was 9 (IQR: 2.5-15.5), MMSE 13 (4-22) and number of medications 8 (5.5-10.5). The mean number of diagnoses per resident was 6.2 (SD: 4). Thirty per cent were malnourished, 66% had evidence of behavioural disturbance. Residents had contact with the NHS on average once per month. CONCLUSION: residents from both residential and nursing settings are dependent, cognitively impaired, have mild frequent behavioural symptoms, multimorbidity, polypharmacy and frequently use NHS resources. Effective care for such a cohort requires broad expertise from multiple disciplines delivered in a co-ordinated and managed way.
Authors Gordon,A. L.;Franklin,M.;Bradshaw,L.;Logan,P.;Elliott,R.;Gladman,J. R.
Publication Year 2014
Journals Age Ageing.
Volume 43
Issue 1
Startpage 97-
Endpage 103
Doi doi:10.1093/ageing/aft077
Link to details 1190
Title Retinopathy, nephropathy, peripheral neuropathy and geriatric scale scores in elderly people with Type 2 diabetes.
Abstract Aims: To analyse the relationships between retinopathy, nephropathy, peripheral neuropathy and geriatric scale scores in elderly people with Type 2 diabetes. Methods: GERODIAB is the first French multi-centre, prospective, observational study designed to assess the influence of glycaemic control on mortality and morbidity through a 5-year follow-up study in people with Type 2 diabetes aged 70 years and older. In this report the relationships at baseline between retinopathy, nephropathy and peripheral neuropathy, and five geriatric scale scores in 987 people, using bivariate and multivariate analyses are analysed. Results: Retinopathy (26%) was significantly associated with impaired scores on the Mini Geriatric Depression Scale, the Mini Nutritional Assessment and the Instrumental Activities of Daily Living scale. Logistic regression showed that the duration of diabetes, BMI, Mini Geriatric Depression Scale, hypoglycaemia and HbA1c were associated with retinopathy (concordance 69.1%; P < 0.001). Nephropathy (47.4%, including 34.8% with Modification of Diet in Renal Disease < 60 ml/min) was significantly associated with impaired Activities of Daily Living and Instrumental Activities of Daily Living scale scores. Using the logistic model, the most significant factors were age, duration of diabetes, triglycerides, HDL cholesterol, hypoglycaemia, hypertension and BMI (concordance 66.3%; P < 0.001). Peripheral neuropathy (28.2%) was associated with impaired scores on the Mini Mental State Examination, Activities of Daily Living, Instrumental Activities of Daily Living and Mini Geriatric Depression Scales. In the logistic model, diastolic blood pressure, duration of diabetes and the Instrumental Activities of Daily Living, Mini Geriatric Depression Scale and Mini Mental State Examination scales were included (concordance 69.8%; P < 0.001). Conclusion: In this specific sample, classical microvascular complications of diabetes were found to be associated with impaired geriatric scale scores. This highlights the benefits of systematic assessment in elderly people with Type 2 diabetes. (copyright) 2013 Diabetes UK.
Authors Le Floch,J. P.;Doucet,J.;Bauduceau,B.;Verny,C.
Publication Year 2014
Journals Diabet Med.
Volume 31
Issue 1
Startpage 107-
Endpage 111
Doi doi:10.1111/dme.12327
Link to details 1191
Title Psychosocial correlates of nutritional status of family caregivers of persons with dementia.
Abstract ABSTRACT Background: This exploratory study investigated the associations of individual characteristics of both persons with dementia and family caregivers with the nutritional status of caregivers. Methods: This cross-sectional study was conducted at home by psychogerontologist within the frame of a community gerontological center in rural areas of south west France. The study participants comprised 56 community-dwelling persons with dementia (mean 80.7 years, SD 6.5) and 56 family caregivers (mean 70.9 years, SD 11.0). Persons with dementia were assessed with Mini-Mental State Examination (MMSE), Basic Activities Of Daily Living (ADL), Instrumental ADL (IADL), and NeuroPsychiatric Inventory (NPI), and family caregivers with the Burden Interview (Zarit scale), the State-Trait Anxiety Inventory (STAI Y-B), the Center for Epidemiologic Studies Depression Scale (CES-D), the emotional impact measure of NPI and the Autonomy, Gerontology and Group Resources scale (AGGIR scale). For both, nutritional status was evaluated using the Mini Nutritional Assessment (MNA(R)). Results: Among family caregivers, 32.1% were at risk of malnutrition and 5.4% were malnourished, and among people with dementia, 58.9% and 23.2%, respectively. NPI severity score of apathy of persons with dementia (Beta = -0.342, p = 0.001), dependency on AGGIR scale (Beta = -0.336, p = 0.002), and CES-D score of caregivers (Beta = -0.365, p = 0.001) were associated with caregivers' MNA score (Adjusted R 2 = 0.480, p < 0.001). Conclusion: These preliminary findings emphasize the need for routine assessment of depressive symptoms, functional and nutritional status in dementia family caregivers, and confirm the value of investigating caregivers' nutritional risk through an integrative view including psychosocial approach.
Authors Rullier,L.;Lagarde,A.;Bouisson,J.;Bergua,V.;Torres,M.;Barberger-Gateau,P.
Publication Year 2014
Journals Int Psychogeriatr.
Volume 26
Issue 1
Startpage 105-
Endpage 113
Doi doi:10.1017/S1041610213001579; 10.1017/S1041610213001579
Link to details 1040
Title Malnutrition: A highly predictive risk factor of short-term mortality in elderly presenting to the emergency department.
Abstract Objectives: To identify independent risk factors of mortality among elderly patients in the 3 months after their visit (T3) to an emergency department (ED). Design: Prospective cohort study. Setting: University hospital ED in an urban setting in France. Participants: One hundred seventy-three patients aged 75 and older were admitted to the ED over two weeks (18.7% of the 924 ED visits). Of these, 164 patients (94.8%) were included in our study, and 157 (95.7%) of them were followed three months after their ED visit. Measurements: During the inclusion period (T0), a standardized questionnaire was used to collect data on socio-demographic and environmental characteristics, ED visit circumstances, medical conditions and geriatric assessment including functional and nutritional status. Three months after the ED visits (T3), patients or their caregivers were interviewed to collect data on vital status, and ED return or hospitalization. Results: Among the 157 patients followed at T3, 14.6% had died, 19.9% had repeated ED visits, and 63.1% had been hospitalized. The two independent predictive factors for mortality within the 3 months after ED visit were: malnutrition screened by the Mini Nutritional Assessment short-form (MNA-SF) (OR=20.2; 95% CI: 5.74-71.35; p<.001) and the Cumulative Illness Rating Scale for Geriatrics (CIRS-G) score (OR=1.1; 95% CI: 1.01-1.22; p=.024). Conclusion: Malnutrition is the strongest independent risk factor predicting short-term mortality in elderly patients visiting the ED, and it was easily detected by MNA-SF and supported from the ED visit. (copyright) 2013 Serdi and Springer-Verlag France.
Authors Gentile,S.;Lacroix,O.;Durand,A. C.;Cretel,E.;Alazia,M.;Sambuc,R.;Bonin-Guillaume,S.
Publication Year 2013
Journals J Nutr Health Aging.
Volume 17
Issue 4
Startpage 290-
Endpage 294
Doi doi:10.1007/s12603-012-0398-0
Link to details 1033
Title Motor and non-motor determinants of chronic fatigue in idiopathic Parkinson's disease (IPD).
Abstract Background: Fatigue is one of themost common non-motor symptoms in patients with Parkinson's disease(PD) with significant impact on quality of life. Fatigue has received increasing attention during recent decade; however, few studies have examined the determinant factors of fatigue and little is known about the relationship between fatigue and other motor and non-motor symptoms. Objective: The aims of this study were to evaluate determinant factors relating to fatigue in PD and to compare the strength of measure of association for different non-motor and motor symptoms with fatigue severity. Patients and methods: This cross-sectional study was performed in a movement disorder clinic in Tehran, Iran during 2011-2012. A total number of 54 PD (38 males and 16 females) patients with the mean age of 62.5 (SD=9.1) yr were recruited. Fatigue was scored using the Fatigue Severity Scale (FSS). Other scales were used including PDQ39 (PD-specific QoL), HADS (anxiety & depression), MNA (mininutritional assessment), Schwab & England (activity of daily living) and Hoehn & Yahr scales (level of disability). Results: Patients' score in fatigue had significant correlation with anxiety (r=0.32, P=0.020), depression (r=0.41, P=0.002), disease severity measured by Hoehn & Yahr scale (r=0.36, P=0.007) and activity of daily living described by Schwab & England scale (r= -0.35, P=0.011). Conclusion: Our findings showed that more severe depression is accompanied with more severe fatigue in PD patients. In addition to motor symptoms of PD, anxiety and depression have noticeable relationship with fatigue, which must be considered in management of fatigue in PD patients.
Authors Fereshtehnejad,S. -M;Shafiei Sabet,M.;Farhadi,F.;Hadizadeh,H.;Khaefpanah,D.;Naderi,N.;Rahmani,A.;Delbari,A.;Shahidi,G. A.;Lokk,J.
Publication Year 2013
Journals J Neurol Sci.
Volume 333
Issue 1
Startpage e82
Endpage [Abstract No: 2457, Abstracts of the XXI World Congress of Neurology, Vienna, Austria, Sept 21-26, 2013]
Doi doi:10.1016/j.jns.2013.07.560
Link to details 1034
Title Adequacy of food consumption and nutritional intake of dependent patients in a home care program.
Abstract Background and Objectives: Malnutrition in dependent patients has a high prevalence and it can decrease the quality of life and increase morbidity and mortality. The aim of this study is to describe the food consumption of dependent patients in a home care program and to analyze their nutrient intake adequacy. Methods: Cross-sectional study carried out in 10 Primary Care Centers of the Reus-Tarragona area. The patients of the Home Care Program were included when they had a score between 17-23.5 in the Mini Nutritional Assessment test (MNA), older than 65 and had caregivers. Food consumption was recorded by a food frequency questionnaire. The SPSS/PC program was used for statistical analysis. Results: 192 patients of the Home Care Program participated with a mean age of 85(plus or minus)7.2 years. The average intake of energy was 1801.5(plus or minus)434.3 kcal/day in men and 1694.86(plus or minus)312.1 kcal/day in women, 75.06% and 90.39% respectively of the Spanish recommended nutrient intake (RNI). The macronutrient distribution is 38.1% carbohydrates, 47.9% lipids and 13% proteins. The protein intake covers 86.4% of the RNI. The mean intakes of vitamin B3, vitamin B6, vitamin D, Ca and Fe are below two-thirds of the RNI. However, the probability of inadequate intake of vitamin B12 (3.15) and vitamin C (16.98) are low. Conclusions: Dependent patients had a diet high in fat and low in carbohydrates. The average intake of energy and proteins was adequate, but the main vitamins and minerals were below of the recommendations, except for vitamin B12 and vitamin C.
Authors Fernandez-Barres,S.;Marti,N.;Armengol,T. C.;Anguera,C.;Castelao-Alvarez,A. I.;Martinez-Blesa,T.;Pedret,R.;Basora,J.;Arija,V.
Publication Year 2013
Journals Ann Nutr Metab.
Volume 62
Issue 2
Startpage 74
Endpage [Poster P146, Mediterranean Foods on Health and Disease, World Forum for Nutrition Research Conference, Reus, Spain, May 20-21, 2013]
Doi doi:10.1159/000351281
Link to details 1035
Title Nutritional intervention in patients with advanced dementia in a psychogeriatrics unit.
Abstract Objective.- To establish the importance of nutritional intervention in patients with advanced dementia. Material and methods.- Assess the effectiveness of specific nutritional intervention, in 8 patients with advanced dementia (100% women, FAST 7e), age (88(plus or minus)9.39 years) and total dependence to ADL MBI 1(plus or minus)1.98 points) after six months of treatment, through the MNA-SF and biochemical markers of malnutrition. Results.- In October 2012, our patient's BMI was 19.11(plus or minus)2.99 points, and the score of the MNA-SF was 7.75(plus or minus)1.29 points, with a prevalence of malnutrition of 62.5%. Note that there is dysphagia (Bedside method) in 62.5% of the patients. After six months of intervention (adapted basic nutrition (diet mixer and hydration with liquids gelatinized or thickened in texture honey (n = 3) and nectar (n = 2) and supplementation with highprotein and high-calorie product and calcifediol), is objectively a gain of 7.2(plus or minus)1.46 kg (BMI 22.21(plus or minus)3.04). After the intervention, the prevalence of malnutrition is 12.5% (MNA-SF 8.88(plus or minus)1.05). Furthermore, we obtained a standardization of analytical parameters of malnutrition such as albumin (3.77(plus or minus)0.24), lymphocytes (1780(plus or minus)185.40), total proteins (6.5(plus or minus)0.36), total cholesterol (208(plus or minus)33.67), transferrin (245.25(plus or minus)22.88) and vitamin D (22.87(plus or minus)9). Conclusions.- Nutrition intervention in patients with advanced dementia decreases the prevalence of malnutrition and improves analytical parameters, minimizing the possibility of problems related to a poor nutritional status.
Authors Fernandez,N.;Martinez,V.;Aurre,I.;Sierra-Sesumaga,I.;Zalduegi,G.;Artaza,I.
Publication Year 2013
Journals Eur Geriatr Med.
Volume 4
Issue 1
Startpage S132
Endpage [Poster P369, 9th Congress of the European Union Geriatric Medicine Society (EUGMS), Venice, Italy, October 2-4, 2013]
Doi doi:10.1016/j.eurger.2013.07.433
Link to details 1036
Title Utility of geriatric assessment to predict mortality in the oldest old: The OCTABAIX study 3-year follow-up.
Abstract Objective: Few studies have prospectively evaluated the utility of geriatric assessment tools as predictors of mortality in the oldest population. We investigated predictors of death in an oldest-old cohort after 3 years of follow-up. Methods: The Octabaix study is a prospective, community-based study with a follow-up period of 3 years involving 328 subjects aged 85 at baseline. Data were collected on functional and cognitive status, co-morbidity, nutritional and falls risk, quality of life, social risk, and long-term drug prescription. Vital status for the total cohort was evaluated after 3 years of follow-up. Results: Mortality after 3 years was 17.3%. Patients who did not survive had significantly poorer baseline functional status for basic and instrumental activities of daily living (Barthel and Lawton Index), higher co-morbidity (Charlson), higher nutritional risk (Mini Nutritional Assessment), higher risk of falls (Tinetti Gait Scale), poor quality of life (visual analog scale of the Quality of Life Test), and higher number of chronic drugs prescribed. Cox regression analysis identified the Lawton Index (hazard ratio [HR] 0.82, 95% confidence interval [CI] 0.73-0.89) and the number of chronic drugs prescribed (HR 1.09, 95% CI 1.01-1.18) as independent predictors of mortality at 3 years. Conclusions: Among the variables studied, the ability to perform instrumental activities of daily living and using few drugs on a chronic basis at baseline are the best predictors of which oldest-old community-dwelling subjects survive after a 3-year follow-up period. (copyright) Mary Ann Liebert, Inc.
Authors Formiga,F.;Ferrer,A.;Chivite,D.;Montero,A.;Sanz,H.;Pujol,R.;Almeda,J.;Badia,T.;Lobato,A.;Fernandez,C.;Ferrer,A.;Formiga,F.;Gil,A.;Megido,M. J.;Padros,G.;Sarro,M.;Tobella,A.
Publication Year 2013
Journals Rejuvenation Res.
Volume 16
Issue 4
Startpage 279-
Endpage 284
Doi doi:10.1089/rej.2013.1422
Link to details 1037
Title Effect of postoperative delirium on quality of life and daily activities 6 month after elective cardiac surgery in the elderly.
Abstract Objectives: Delirium after surgery is known to have an influence on mortality, length of hospital stay and nursing home placement. Especially elderly patients are concerned about losing independence or ending up in a care facility. The aim of the study was to examine the influence of postoperative delirium on quality of life (QOL) and daily activities six month after cardiac surgery in elderly patients. Methods: 183 patients (greater-than or equal to)70 years undergoing elective coronary artery bypass and/or valve surgery between December 2010 and February 2012 were involved in this prospective study. Delirium was validated by Confusion Assessment Method for the ICU (CAM-ICU). The following tests were performed six months after surgery: Activities of Daily Living (IADL), Barthel index, Nuremberg Age Activity List (NAA), quality of life (SF-12: physical and mental component score; PCS/MCS), Minimal Nutritional Assessment (MNA) and Geriatric Depression Scale (GDS). The effect of postoperative delirium was measured by analysis of covariance. Results: Sixty patients (32.8%) developed a delirium. These patients had lower QOL concerning PCS (delirium 39.0 vs. no delirium 43.3; p = 0.009), and MCS (delirium 48.8 vs. no delirium 52.4; p = 0.02). Patients who had no delirium postoperatively showed higher levels of activity of daily living: Barthel index (99.1 vs. 94.0; p = 0.001), IADL (6.8 vs. 6.2; p = 0.036), NAA (26.9 vs. 29.3; p = 0.016). Patients with delirium had a lower level of nutrition (MNA: 25.3 vs. 26.4; p = 0.03). There were no differences between groups with regard to depression (GDS: with delirium 2.9 vs. 2.5 without delirium; p = 0.339). Conclusions: Postoperative delirium seems to have a negative effect on quality of life and level of daily activities six month after cardiac surgery in the elderly. Prevention of postoperative delirium may ameliorate the quality of live after surgery. Further studies are needed to confirm these data.
Authors Freibrodt,J.;Huppe,M.;Sedemund-Adib,B.;Sievers,H. H.;Schmidtke,C.
Publication Year 2013
Journals Thorac Cardiovasc Surg.
Volume 61
Issue 1
Endpage Abstract, 42nd Annual Meeting of the German Society for Cardiovascular and Thoracic Surgery, Freiburg, Germany, February 17-20, 2013]
Doi doi:10.1055/s-0032-1332732